The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells.

By Shilpa Gandre-Babbe, A. M. van der Bliek. Molecular Biology of the Cell, 2008

771 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a559aafbae5fcf1640be81b17a5f8acf7522a0da

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In Molecular Biology

1. Douglas R. Green
2. D. C. Chan
3. B. Westermann
4. Orian Shirihai
5. Hsiuchen Chen
6. M. Liesa
7. F. Llambi
8. W. Ding

Citations in the corpus

• Mitochondrial dynamics in mammalian health and disease. (2009, background): “However, Mff is located in the outer mitochondrial membrane and not in the same complexes as Fis1, thereby suggesting an independent role of Mff in fission (106).”
• Mitophagy: mechanisms, pathophysiological roles, and analysis (2012, background): “The levels of the decreased mitochondrial proteins were strongly correlated with citrate synthase activity (Gegg et al. , 2010 ).”
• Mitochondrial dynamics–fusion, fission, movement, and mitophagy–in neurodegenerative diseases (2009, background): “Knockdown of Mff causes mitochondrial elongation and resistance to CCCP-induced fragmentation (24).”
• Mitochondrial dynamics and mitochondrial quality control (2014, background): “Mitochondrial fission and fusion and motility in mitophagy Mitochondria are dynamic organelles that continuously undergo fission and fusion, which are necessary for cell survival and adaptation to changing conditions needed for cell growth, division, and distribution of mitochondria during…”
• The BCL-2 Family Reunion (2010, background): “Indeed, loss of DRP-1 or Mff function by RNAi, a dominant-negative DRP1, or pharmacological inhibition of DRP-1 delays MOMP, mitochondrial fragmentation, and apoptosis (Cassidy-Stone et al., 2008; Frank et al., 2001; Gandre-Babbe and van der Bliek, 2008; Lee et al., 2004).”
• Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure (2013, background): “Of note, Drp1, Fis1, and Mff also control peroxisomal fission (Schrader, 2006; Waterham et al., 2007; Gandre-Babbe and van der Bliek, 2008).”