Daniel L. Kastner

Molecular Biology · 2002–2020

A researcher in the Science corpus: 14 papers; trusts 1 researcher and is trusted by 1 researcher here, as inferred from the citation graph.

Subfields

• Molecular Biology — 109 citations into it; #12,376 of 17,773 by trust here, #3,138 by citations

Whom Daniel L. Kastner trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. J. Tschopp

Who trusts Daniel L. Kastner overall

1. C. A. Dinarello

Papers from Daniel L. Kastner's perspective

Ordered by how strongly the researchers Daniel L. Kastner trusts endorse each paper. Same corpus, a different order for every researcher.

1. Gout-associated uric acid crystals activate the NALP3 inflammasome (Nature)
2. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease (Nature)
3. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease (Nature)
4. The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation (Cell Death and Differentiation)
5. NALP1 in vitiligo-associated multiple autoimmune disease. (New England Journal of Medicine)
6. Critical Role for Cryopyrin/Nalp3 in Activation of Caspase-1 in Response to Viral Infection and Double-stranded RNA*> (Journal of Biological Chemistry)
7. Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation. (Molecules and Cells)
8. Nod2 Mutation in Crohn's Disease Potentiates NF-κB Activity and IL-1ß Processing (Science)
9. Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes. (American Journal of Human Genetics)
10. A new multipoint method for genome-wide association studies by imputation of genotypes (Nature Genetics)

Their papers

• A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. (2004) — 1,595 citations
• Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*). (2009) — 1,096 citations
• Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS) (2011) — 844 citations
• A small molecule inhibitior of the NLRP3 inflammasome is a potential therapeutic for inflammatory diseases (2015) — 2,420 citations
• De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases. (2002) — 716 citations
• The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP (2012) — 987 citations
• Activated STING in a Vascular and Pulmonary Syndrome (2014) — 1,198 citations
• A guiding map for inflammation (2017) — 661 citations
• Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease (2020) — 871 citations
• Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2 (2014) — 757 citations
• Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci (2010) — 1,367 citations
• STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. (2007) — 1,095 citations
• TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study. (2007) — 821 citations
• Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4. (2005) — 611 citations