J. Clarke
Molecular Biology · with Irvine · 2012–2022
A researcher in the Science corpus: 7 papers; trusts 1 researcher and is trusted by 0 researchers here, as inferred from the citation graph.
Subfields
- Molecular Biology — 66 citations into it
- Cell Biology — 33 citations into it
- Epidemiology — 28 citations into it
Whom J. Clarke trusts
Their strongest outbound trust, strongest first, inferred from their citations.
- J. Backer (in Molecular Biology)
Papers from J. Clarke's perspective
Ordered by how strongly the researchers J. Clarke trusts endorse each paper. Same corpus, a different order for every researcher.
- Increased Insulin Sensitivity and Reduced Adiposity in Phosphatidylinositol 5-Phosphate 4-Kinase β−/− Mice
- Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex (Science)
- Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase. (Proceedings of the National Academy of Sciences of the United States of America)
- Structure of type IIbeta phosphatidylinositol phosphate kinase: a protein kinase fold flattened for interfacial phosphorylation.
- LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing (EMBO Journal)
- In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. (Molecular Biology of the Cell)
- Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. (Molecules and Cells)
- Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation (Autophagy)
- Regulation of cellular growth by the Drosophila target of rapamycin dTOR. (Genes & Development)
- The activation loop of phosphatidylinositol phosphate kinases determines signaling specificity.
Their papers
- Phosphatidylinositol 5-phosphate 4-kinase (PIP4K) regulates TOR signaling and cell growth during Drosophila development (2013) — 71 citations
- In B cells, phosphatidylinositol 5-phosphate 4-kinase–α synthesizes PI(4,5)P2 to impact mTORC2 and Akt signaling (2016) — 30 citations
- Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization (2013) — 62 citations
- Development of Selective Phosphatidylinositol 5-Phosphate 4-Kinase γ Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode (2022) — 15 citations
- Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein (2017) — 54 citations
- PI(5)P Regulates Autophagosome Biogenesis (2015) — 245 citations
- The activity, evolution and association of phosphatidylinositol 5-phosphate 4-kinases. (2012) — 40 citations