Innate IL-17-producing cells: the sentinels of the immune system

By D. Cua, C. Tato. Nature reviews. Immunology, 2010

1,018 citations recorded by the source corpus.

Subfields: Immunology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/d35a038e8a3dce01517180b381353dc4a15e5f37

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. D. Cua
2. S. Gaffen
3. C. Tato
4. D. Artis
5. A. Garg
6. Nilesh Amatya
7. K. Futosi
8. Szabina Fodor

In Pathology and Forensic Medicine

1. D. Cua
2. C. Tato
3. S. Gaffen
4. A. Garg
5. Nilesh Amatya

Citations in the corpus

• The Microbiome in Infectious Disease and Inflammation (2012, neutral): “These cells include, but are likely not limited to, NK-like NKp46+ cells, LTi-like cells, and Thy1highSCA1+Lin−Kit−CD3−CD4− cells (27, 191).”
• Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in mice (2016, neutral): “Therap Adv Gastroenterol 6(4):295–308.”
• The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells (2011, background): “Although it is clear that RORgt+ ILCs play an important role in gut immunity (Colonna, 2009; Cua and Tato, 2010), transcriptional regulation of RORgt+ ILCs remains to be determined.”
• Netting neutrophils induce endothelial damage, infiltrate tissues and expose immunostimulatory molecules in systemic lupus erythematosus (2011, background): “Innate IL-17–producing cells are considered an integral part of IL17–mediated immune responses (26).”
• Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis (2011, background): “Although IL-17 production by T cells is widely studied, it is increasingly appreciated that diverse types of innate immune cells also can produce IL-17 (17).”
• CD4+ lymphoid tissue inducer cells promote innate immunity in the gut (2010, background): “…in promoting innate immunity and intestinal inflammation via production of host protective and/or inflammatory cytokines (Buonocore et al., 2010; Cella et al., 2009; Colonna, 2009; Cua and Tato, 2010; Eberl et al., 2004; Satoh-Takayama et al., 2008; Sawa et al., 2010; Spits and Di Santo, 2010).”
• IL-17 Signaling: The Yin and the Yang (2017, background): “Furthermore, IL-17-expressing Type 3 “innate lymphoid cells” (ILC3) have been described, which lack an antigen receptor and serve as the innate counterparts of Th17 cells [6].”
• IL-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability (2015, positive): “Thus, given their ability to rapidly respond to proteins and inflammatory cytokines (Cua and Tato, 2010), gd T cells, as opposed to ILC3s, are important in maintaining epithelial integrity in our model through the secretion of IL-17.”
• Neutrophil cell surface receptors and their intracellular signal transduction pathways (2013, background): “Further details on TGFβ-receptor signal transduction [178,179] and IL17-mediated inflammatory responses and IL-17 receptor signaling [180–184] can be found in excellent recent reviews.”
• Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation. (2011, neutral): “It is possible that AhR, although not essential for the survival, development, or migration of other cell types, is important for their function, for example, for the induced production of IL-22 in Th17 cells or in populations of innate lymphoid cells (Cua and Tato, 2010; Veldhoen et al., 2008) that”