The intestinal epithelial stem cell.

By E. Marshman, C. Booth, C. Potten. Bioessays, 2002

621 citations recorded by the source corpus.

Subfields: Genetics, Hepatology, Oncology

View Paper: https://www.semanticscholar.org/paper/f5ac49701742aeffe4ab013b8107ef538dd6ad52

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. Hans Clevers
2. A. Gregorieff
3. H. Begthel
4. Thomas Brabletz
5. F. Doetsch
6. Nick Barker
7. R. Nusse
8. Pengfei Lu

In Hepatology

1. Hans Clevers

In Oncology

1. Hans Clevers
2. F. Doetsch
3. H. Begthel
4. Thomas Brabletz
5. R. Weinberg
6. R. Nusse
7. C. Blanpain
8. Nick Barker

Citations in the corpus

• Brain micro-ecologies: neural stem cell niches in the adult mammalian brain (2008, background): “Interestingly, studies from several niches have revealed that transit-amplifying cells also retain the ability to act as stem cells when challenged by appropriate stimulation (Doetsch et al. 2002; Marshman et al. 2002; Raff 2003; Brawley & Matunis 2004; Kai & Spradling 2004).”
• The intestinal crypt, a prototype stem cell compartment. (2013, background): “Thus, the LRC trait of position 4 cells does not reflect quiescence but, rather, is proposed to result from asymmetric segregation of old (labeled) and new (unlabeled) DNA strands into stem cells and their daughters respectively (Marshman et al., 2002; Potten et al., 2002).”
• Wnt signalling induces maturation of Paneth cells in intestinal crypts (2005, background): “The canonical Wnt signalling cascade is known to control multiple biological phenomena in vertebrates and model organisms, involving either cell-fate determination or maintenance of stem/progenitor cells in compartments with predefined fate”
• DNA damage response and cellular senescence in tissues of aging mice (2009, background): “Foci-positive cells were clustered in an area slightly above the bottom of the crypt, which is known to contain the fast proliferating, transiently amplifying enterocytes derived from the stem cells that reside close to the crypt base (Marshman et al., 2002).”
• Wnt signaling in the intestinal epithelium: from endoderm to cancer. (2005, background): “The self-renewing capacity of the intestine depends on the existence of stem cells (Marshman et al. 2002; Pinto and Clevers 2005).”
• The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength (2014, neutral): “TA cells rapidly divide four to five times prior to their differentiation upon crossing the crypt villus junction (Marshman et al. 2002).”