Identification and characterization of metabolically benign obesity in humans.

By N. Stefan, K. Kantartzis, J. Machann, F. Schick, C. Thamer, K. Rittig, B. Balletshofer, F. Machicao, A. Fritsche, H. Häring. Archives of Internal Medicine, 2008

1,090 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Epidemiology, Physiology

View Paper: https://www.semanticscholar.org/paper/eaf10ad85143a579aeac1186997ec1367331c889

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrinology, Diabetes and Metabolism

1. M. Blüher
2. George P. Chrousos
3. G. Kaltsas
4. E. Kassi
5. Panagiota Pervanidou
6. B. Zinman
7. Gerald I. Shulman
8. V. Samuel

In Epidemiology

1. M. Blüher
2. R. Retnakaran
3. C. Kramer
4. E. Brunt
5. Gerald I. Shulman
6. V. Samuel

In Physiology

1. J. Kirkland
2. T. Tchkonia
3. M. Blüher
4. Yi Zhu
5. George P. Chrousos
6. M. Flinn

Citations in the corpus

• Insulin-sensitive obesity. (2010, background): “However, previous studies have shown that amount of visceral fat correlates with intrahepatic triglyceride, intramyocellular lipid content, and epicardial fat (18, 38, 44), suggesting analogous relationships between other ectopic fat depots and insulin sensitivity, as we observed for visceral fat.”
• Non-invasive assessment and quantification of liver steatosis by ultrasound, computed tomography and magnetic resonance. (2009, background): “Of particular interest, in obese subjects fatty liver appears to be a stronger determinant of insulin resistance and earlier markers of atherosclerosis than total and visceral adiposity [7].”
• Nonalcoholic fatty liver disease: pathology and pathogenesis. (2010, background): “(100) characterized metabolically benign obesity by studying normal, overweight, and obese adults.”
• Metabolically Healthy Obesity (2020, background): “In a large BMI-stratified cohort, Stefan et al (20, 23) linked high liver fat content and predominantly abdominal (including visceral) adiposity to MUO, whereas greater insulin sensitivity, better insulin secretion, cardiorespiratory fitness, and lower body subcutaneous fat mass were associated wit”
• Metabolic syndrome: definitions and controversies (2011, background): “Obesity/insulin resistance and MetS Although not all overweight or obese individuals are metabolically disturbed, the majority are IR [69-71].”
• Chronic Inflammation in Obesity and the Metabolic Syndrome (2010, neutral): “[9] N.”
• Are Metabolically Healthy Overweight and Obesity Benign Conditions? (2013, background): “Although these clinical outcomes occurred only after long-term follow-up, it should be noted that, regardless of metabolic status, excess weight is associated in the short term with subclinical vascular disease, including impaired vasoreactivity (51), abnormalities in left ventricular measures (41, ”
• Mechanisms and Metabolic Implications of Regional Differences among Fat Depots (2013, background): “…responsiveness, and lipolysis; increased secretion of some adipokines (e.g., leptin) and decreased secretion of others (e.g., PAI-1); and changes in extracellular matrix component production, microRNAs, histones, and chromatin structure (reviewed in Cristancho and Lazar, 2011; Tang and Lane, 2012).”