Metabolic syndrome: definitions and controversies
By E. Kassi, Panagiota Pervanidou, G. Kaltsas, George P. Chrousos. BMC Medicine, 2011
1,446 citations recorded by the source corpus.
Metabolic syndrome (MetS) is a complex disorder defined by a cluster of interconnected factors that increase the risk of cardiovascular atherosclerotic diseases and diabetes mellitus type 2. Currently, several different definitions of MetS exist, causing substantial confusion as to whether they identify the same individuals or represent a surrogate of risk factors. Recently, a number of other factors besides those traditionally used to define MetS that are also linked to the syndrome have been identified. In this review, we critically consider existing definitions and evolving information, and conclude that there is still a need to develop uniform criteria to define MetS, so as to enable comparisons between different studies and to better identify patients at risk. As the application of the MetS model has not been fully validated in children and adolescents as yet, and because of its alarmingly increasing prevalence in this population, we suggest that diagnosis, prevention and treatment in this age group should better focus on established risk factors rather than the diagnosis of MetS.
Subfields: Endocrinology, Diabetes and Metabolism, Epidemiology
View Paper: https://www.semanticscholar.org/paper/0daaaf87aa39f6709889df720cf0685c84d0597c
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In Endocrinology, Diabetes and Metabolism
Citations in the corpus
- Prevalence and trends of metabolic syndrome among adults in the asia-pacific region: a systematic review (2017, background): “However, it is generally accepted that no matter which criteria are used, the prevalence of MetS is high and rising in most counties as a result of the obesity epidemic [41].”
- Chlorogenic Acid: Recent Advances on Its Dual Role as a Food Additive and a Nutraceutical against Metabolic Syndrome (2017, background): “Its components include dyslipidemia (elevated plasma total cholesterol, low-density lipoproteins (LDL), and triglycerides, and low levels of high-density lipoproteins (HDL)), high blood pressure, high fasting blood glucose levels, insulin resistance, chronic proinflammatory and prothrombotic states,”
- Psoriasis and Comorbid Diseases Part I. Epidemiology (2017, neutral): “Metabolic syndrome Metabolic syndrome is generally defined by the presence of a combination of central obesity, hypertension, insulin resistance, and dyslipidemia.(88) Studies have found metabolic syndrome and its individual components tobemoreprevalent amongpatientswith than without psoriasis in bo”