The Arabidopsis Receptor Kinase FLS2 Binds flg22 and Determines the Specificity of Flagellin Perception[W]

By D. Chinchilla, Zsuzsa Bauer, M. Regenass, T. Boller, G. Felix. The Plant Cell Online, 2005

869 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/d9230a89258752812d6b64037a2438cee0cb29a1

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Citations in the corpus

Signaling in Plant-Microbe Interactions (2013, background): “A 22-amino acid epitope (flg22) present in the flagellin N-terminus is enough to activate the Arabidopsis FLS2 receptor (Chinchilla et al. 2006).”
Rhizobacteria-induced systemic resistance (2009, background): “In Arabidopsis, flagellin is perceived through its direct interaction with the transmembrane leucine-rich-repeat receptor kinase (LRR-RK) FLS2 (Chinchilla et al., 2006).”
Phyllospheric Microbiomes: Diversity, Ecological Significance, and Biotechnological Applications (2020, background): “For example, the flagellin-sensitive receptor 2 (FLS2) is a pattern receptor which recognizes the P. syringae pathovar (pv.) bacterial flagellin (flg22) (Chinchilla et al.”
Of PAMPs and Effectors: The Blurred PTI-ETI Dichotomy[OA] (2011, background): “By contrast, interfamily transfer of PAMP receptors appears to be more successful, as exemplified by the transfer of the PRRs EFR for bacterial EF-Tu and FLS2 for bacterial flagellin from Arabidopsis toN. benthamiana and tomato (Chinchilla et al., 2006; Zipfel et al., 2006; Lacombe et al., 2010).”
Bacterial effectors target the common signaling partner BAK1 to disrupt multiple MAMP receptor-signaling complexes and impede plant immunity. (2008, background): “Affinity-crosslinking assays demonstrated direct binding of flagellin with FLS2 and EF-Tu with EFR, respectively (Chinchilla et al., 2006; Zipfel et al., 2006).”
The Arabidopsis NPR1 protein is a receptor for the plant defense hormone salicylic acid. (2012, background): “The subsequent report of the specific interaction between flg22 and FLS2 indicates that the FLS2 protein is the bona fide receptor for flg22 (Chinchilla et al., 2006).”
Ligand-induced endocytosis of the pattern recognition receptor FLS2 in Arabidopsis. (2006, background): “Arabidopsis FLS2 mediates flagellin recognition on the basis of the highly conserved flg22 peptide (Gomez-Gomez et al. 2001; Chinchilla et al. 2006).”
Molecular communication in the rhizosphere (2009, background): “thaliana (Chinchilla et al. 2006; Zipfel et al. 2006).”
Impact of root exudates and plant defense signaling on bacterial communities in the rhizosphere. A review (2011, background): “However, Vicré et al. (2005) observed a different organization of border cells in Arabidopsis, which are therefore designated as border-like cells.”
The FLS2-associated kinase BIK1 directly phosphorylates the NADPH oxidase RbohD to control plant immunity. (2014, background): “A major class of the plant immune receptors are the cell surface-localized pattern-recognition receptors (PRRs) that detect conserved microbial molecular patterns, such as fungal chitin or bacterial lipopolysaccharides, peptidoglycans, elongation factor-Tu, and flagellin, and trigger an array of def”
The Arabidopsis Leucine-Rich Repeat Receptor–Like Kinases BAK1/SERK3 and BKK1/SERK4 Are Required for Innate Immunity to Hemibiotrophic and Biotrophic Pathogens[W] (2011, background): “InArabidopsis thaliana, the best-studied PRRs are the leucinerich repeat receptor kinases (LRR-RKs) FLAGELLIN SENSING2 (FLS2) and EF-TU RECEPTOR (EFR) that specifically bind the bacterial peptide PAMPs flg22 (derived from flagellin) and elf18/ elf26 (derived from elongation factor Tu), respectively ”
Elicitors, effectors, and R genes: the new paradigm and a lifetime supply of questions. (2007, background): “The paradigm of direct interaction between ligand and LRR is well established for transmembrane LRR receptors and is the likely mechanism by which Arabidopsis FLS2 binds flagellin (30).”