Functional significance of adult neurogenesis.

By Gerd Kempermann, Laurenz Wiskott, Fred H. Gage. 2004

654 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. Fred H. Gage
2. Hongjun Song
3. James Bradley Aimone
4. Guo-li Ming
5. Wei Deng
6. E. Gould
7. S. Ge
8. Gerd Kempermann

In Developmental Neuroscience

1. Fred H. Gage
2. Hongjun Song
3. Guo-li Ming
4. James Bradley Aimone
5. Wei Deng
6. E. Gould
7. B. Leuner
8. S. Ge

Citations in the corpus

• New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? (2010, positive): “Computational models of adult-born DGC function As adult neurogenesis has become more widely appreciated as an important form of hippocampal plasticity, its potential to affect learning and memory has been increasingly recognize”
• Adult neurogenesis and cellular brain repair with neural progenitors, precursors and stem cells (2006, background): “During this early postmitotic stage, the new neurons are apparently recruited into a functional role, or die (Kempermann et al. 2004a,b).”
• Potential role for adult neurogenesis in the encoding of time in new memories (2006, background): “By considering the dentate gyrus's theorized role in hippocampal processing, we are able to make specific predictions about how immature neurons may be affecting hippocampus-dependent learning and memory formatio”
• Financial volatility trading using a self-organising neural-fuzzy semantic network and option straddle-based approach (2010, neutral): “Particularly, the human hippocampal formation is capable of a neurogenesis process (Kempermann, Wiskott, & Gage, 2004 ) that has been regarded as the primary mechanism used to 4 In batch learning, it is assumed that all the training data has been collected and is available to the training process.”
• Epigenetic choreographers of neurogenesis in the adult mammalian brain (2010, background): “Principal dentate granule cells are the only neuronal subtype that is generated, and newly generated neurons have distinct properties that enable them to contribute to specialized functions in learning and memor”
• Temporal Discontiguity Is neither Necessary nor Sufficient for Learning-Induced Effects on Adult Neurogenesis (2006, background): “In the dentate gyrus of the adult rat, neurogenesis has been related to various types of learning and memory (Kempermann et al., 2004; Becker, 2005; Leuner et al., 2006), and learning certain tasks can alter the number of new neurons (Gould et al.”
• A critical period for enhanced synaptic plasticity in newly generated neurons of the adult brain. (2007, positive): “Are these new neurons merely replacing dying mature neurons, or are they making unique contributions to specific brain functions that could not be achieved by existing mature neurons? Accumulating evidence from behavioral analysis suggests that adult neurogenesis is essential for some forms of learn”
• New neurons in the dentate gyrus are involved in the expression of enhanced long‐term memory following environmental enrichment (2005, background): “Functionally, these findings support one current view that newborn cells may increase the ability for future learning by providing more cells available for recruitment into existing circuits (for reviews see Gould et al., 1999b; Gross, 2000; Kempermann et al., 2004; Shors, 2004).”
• Temporal and Spatial Dynamics of Brain Structure Changes during Extensive Learning (2006, result): “, 1998; Kempermann and Gage, 1998; Gage, 2002), one could argue that the changes seen in the hippocampus in our study may in fact resemble the exciting neural changes seen in rodents (Gould et al., 1999; van Praag et al., 1999, 2002; Shors et al., 2001; Kempermann et al., 2004).”
• Synaptic integration and plasticity of new neurons in the adult hippocampus (2008, background): “In particular, studies using bromodeoxyuridine (BrdU)-based birth-dating and immunohistochemistry of cell type specific markers have identified a series of intermediate developmental stages during adult neurogenesis (Kempermann et al. 2004a).”
• Adult neurogenesis and functional plasticity in neuronal circuits (2006, background): “The degree of post-developmental neurogenesis in a given species might depend on a trade-off between the benefits accrued from newborn neurons and the problems they generate for the network circuitry into which they integrat”