Chromosome territories--a functional nuclear landscape.

By Thomas Cremer, M. Cremer, S. Dietzel, S. Müller, Irina Solovei, S. Fakan. Current Opinion in Cell Biology, 2006

608 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/c8b28c3d4db236285fcdd1e04eb2814537b741eb

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

Citations in the corpus

Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions (2007, background): “It is now also known that individual chromosomes occupy distinct positions in the nucleus, referred to as chromosome territorie”
Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin. (2008, unknown): “Beside heterochromatin, entire chromosomes are also organized into welldefined regions or territories within mammalian nuclei (Cremer et al. 2006).”
Nuclear Receptor-Induced Chromosomal Proximity and DNA Breaks Underlie Specific Translocations in Cancer (2009, unknown): “Liganded AR Induces Intra- and Interchromosomal Interactions Required for Translocations On the basis of the dynamic reorganization of chromosomes during development or in response to specific signals ( Cremer et al., 2006 ), we investigated whether one role of AR might be to mediate androgen-depend”
Biogenesis and Function of Nuclear Bodies (2011, background): “Individual chromosomes reside in limited and nonrandom regions of the interphase nucleus, known as chromosome territories (Box 1) [1, 2].”
Nuclear organization of the genome and the potential for gene regulation (2007, background): “The idea that the chromosome territory is a unit of nuclear organization was advanced with the suggestion that chromosomes are discrete nuclear bodies separated by an interchromatin compartment — a more or less continuous space between adjacent chromosome”
The impact of translocations and gene fusions on cancer causation (2007, background): “How do gene fusions arise? The three-dimensional chromosome architecture within the interphase nucleus is probably pivotal to the occurrence of gene fusions, particularly the spatial proximity of the genes involve”
Beyond the sequence: cellular organization of genome function. (2007, unknown): “In fact, the observation that the chromosomepositioning patterns are not well conserved between cells in a population but are largely probabilistic suggests that no such mechanisms exist (Parada and Misteli, 2002; Cremer et al., 2006).”