Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions

By C. Lanctôt, T. Cheutin, M. Cremer, Giacomo Cavalli, Thomas Cremer. Nature reviews genetics, 2007

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View Paper: https://www.semanticscholar.org/paper/7ed2fe5fd8336de310298fcfafd9419e9e8e1e10

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Citations in the corpus

A Three-Dimensional Model of the Yeast Genome (2010, background): “2a, Supplementary Tables 1 and 2 and Supplementary Methods); (2) restriction site-based biases (Fig.”
Nuclear architecture of rod photoreceptor cells adapts to vision in mammalian evolution. (2009, background): “Specific nuclear positions ensuring spatial separation of transcriptionally active and inactive chromatin (Kosak et al., 2007; Lanctot et al., 2007), as well as direct spatial nuclear interactions between genes (Fraser and Bickmore, 2007; Sexton et al.”
Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells (2009, background): “496" language="eng" relation="no"> Increasing evidence suggests that long-range interactions between genomic regions contribute to the regulation of gene expressio”
Universal proximity effect in target search kinetics in the few-encounter limit (2016, result): “) observed in different experiments [27,30,33,34], our results provide an explanation of the robustness of the proximity effect for efficient and precise transcription regulation.”
Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin. (2008, neutral): “Positions within these territories appear to be related to the control of gene expression and other nuclear activities (Fraser and Bickmore 2007; Lanctot et al. 2007).”
ChIA-PET tool for comprehensive chromatin interaction analysis with paired-end tag sequencing (2010, background): “Rationale Transcription factors and their three-dimensional interactions are crucial to gene regulation [1,2].”
Spatial coordination between cell and nuclear shape within micropatterned endothelial cells (2012, background): “, which is emerging as a potential regulator of genome functio”
Three-dimensional folding and functional organization principles of the Drosophila genome. (2012, background): “Consistent with the idea of constrained chromosomal territories (Cremer and Cremer, 2010; Lanctôt et al., 2007), the frequency of interarm contacts (2L-2R and 3L-3R) is on average similar to the intensity of the most distal intraarm contacts, and interchromosomal contacts are on average 4-fold…”
Architectural protein subclasses shape 3D organization of genomes during lineage commitment. (2013, positive): “Seminal microscopy studies have linked the spatial positioning of specific genomic loci to gene expression (Fraser and Bickmore, 2007; Kosak and Groudine, 2004; Lanctôt et al., 2007), replication (Gilbert et al.”
Chromatin remodelling during development (2010, neutral): “It is also becoming clear that nuclear architecture and gene positioning contribute to gene regulation (see ref”
CTCF: Master Weaver of the Genome (2009, positive): “In addition to chromatin structure, emerging evidence suggests that spatial positioning of genomic segments within the three-dimensional nuclear space also has an important influence on genome function (Fraser and Bickmore, 2007; Lanctot et al., 2007).”