The Phenolic Hydroxyl Group of Carvacrol Is Essential for Action against the Food-Borne Pathogen Bacillus cereus

By A. Ultee, M. Bennik, R. Moezelaar. Applied and Environmental Microbiology, 2002

1,678 citations recorded by the source corpus.

Subfields: Food Science, Molecular Biology, Pharmacology

View Paper: https://www.semanticscholar.org/paper/c83d76e4663712a519685ae96698f6b6c0294cef

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Food Science

1. Iraj Rasooli
2. S. Ibrahim
3. P. Negi
4. T. Mygind
5. A. Edris
6. R. Meyer
7. M. Hyldgaard
8. I. Kim

In Molecular Biology

1. S. Ibrahim
2. Iraj Rasooli
3. M. Iriti
4. A. Edris

In Pharmacology

1. Iraj Rasooli
2. T. Mygind
3. R. Meyer
4. M. Hyldgaard
5. P. Negi
6. S. Burt
7. A. Edris

Citations in the corpus

• Effect of Monoterpenes on Lipid Composition and Sclerotial Development of Sclerotium cepivorum Berk. (2006, result): “The higher activity displayed by the alcoholic and phenolic monoterpenes in terms of MIC, agrees with previous results on a general structure fungitoxicity relationship, where the presence of alcoholic or phenolic hydroxyl groups appear to be an essential factor for the monoterpenes to exhibit stron”
• The antibacterial mechanism of carvacrol and thymol against Escherichia coli (2008, methodology): “Compared with some traditional methods used in the studies of antibacterial mechanism, like spectrofluorometer (Ultee et al. 1999, 2002), scanning electron microscope (Kwon et al. 2003) and confocal laser scanning microscopy (Gill and Holley 2006), flow cytometry could locate not only specific…”
• A review of plant-derived essential oils in ruminant nutrition and production (2008, background): “In general, phenolic compounds have been shown to have high antimicrobial activity due to the presence of a hydroxyl groups within the phenolic structure (Dorman and Deans, 2000; Ultee et al., 2002; Burt, 2004).”
• Structure and mechanical properties of sodium and calcium caseinate edible active films with carvacrol (2013, background): “If considering that the pKa of phenolic compounds such as carvacrol is around 10, the hydroxyl group should be present (Ultee et al., 2002).”
• Essential Oils and Antifungal Activity (2017, background): “It is possible that carvacrol is capable to bind to the sterols of the fungal membrane, a fact that results in damage and, consequently, death of the fungus [51].”
• Biological Activities of Essential Oils: From Plant Chemoecology to Traditional Healing Systems (2017, background): “As a result of membrane permeabilization, all other cellular functions including membrane potential, efflux pump activity or respiratory activity are also compromised [37,42,43].”
• Phytobiotics in poultry and swine nutrition – a review (2017, background): “For example, studies have showed some of the common terpenoids (e.g. carvacrol and thymol), have similar antimicrobial effects but their action against Gþ or G bacteria is different based on the locations of one or more functional groups in their molecules (Lambert et al. 2001; Ultee et al. 2002).”
• Invited review: Essential oils as modifiers of rumen microbial fermentation. (2007, background): “Hypothesized mechanism of action of carvacrol in the cytoplasmic membrane (Ultee et al., 2002).”