Clinical prevention of sudden cardiac death by n-3 polyunsaturated fatty acids and mechanism of prevention of arrhythmias by n-3 fish oils.

By A. Leaf, J. Kang, Yong‐Fu Xiao, G. Billman. Circulation, 2003

645 citations recorded by the source corpus.

Subfields: Biochemistry, Nutrition and Dietetics, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/bc1ce7e5954da6c36abfc334ce0befe43c68f263

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Citations in the corpus

ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: A report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (2006, neutral): “humans.(261) However, data are conflicting.”
The Omega-3 Index: a new risk factor for death from coronary heart disease? (2004, methodology): “Consistency of epidemiological data Between populations—Yes [30,46,47] Within populations—Yes [9,48] Prospective cohorts—Yes [5,6,20,21,49–56] Strong association between biomarker and disease—Yes [5] Independence from other known risk factors—Yes [5,9] Biological plausibility—Yes [23] Modifiable (Sa”
Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events. (2011, background): “Such effects might contribute to reduced myocyte excitability and cytosolic calcium fluctuations, particularly in ischemic or damaged cells susceptible to partial depolarization and triggered arrhythmia (56).”
Fish intake, contaminants, and human health: evaluating the risks and the benefits. (2006, background): “n-3 PUFAs influence several cardiovascular risk factors.(18,19,43,49,50,60-75,79-84) Effects occur within weeks of intake and may result from altered membrane fluidity and receptor responses following incorporation of n-3 PUFAs into cell membranes(76,77) and direct binding of n-3 PUFAs to intracellu”
The Various Roles of Fatty Acids (2018, background): “mode of action explaining the cardioprotective effects of EPA and DHA, several mechanisms have been proposed: preventing arrhythmias [205,206], lowering plasma triacylglycerol [207], preventing chronic intermittent hypoxia-induced atherosclerosis [208], decreasing arterial cholesterol delivery and p”
n-3 fatty acids and cardiovascular disease. (2006, background): “Leaf et al (33) showed that adding EPA or DHA to cultured neonatal rat cardiomyocytes slows the beating rate and inhibits the induction of tachyarrhythmias by extracellular calcium, ouabain, isoproterenol, lysophosphatidylcholine and acylcarnitine, thromboxane, and the calcium ionophore A23187.”