Computational and experimental identification of C. elegans microRNAs.

By Yonatan H. Grad, John D Aach, Gabriel D. Hayes, B. Reinhart, George M. Church, Gary Ruvkun, John K. Kim. Molecules and Cells, 2003

299 citations recorded by the source corpus.

Subfields: Aging, Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/b48b481eec32a3c11ad1ba85a3109c0a1de6d285

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Citations in the corpus

Identification of Drosophila MicroRNA Targets (2003, background): “Combining these data with computational cross-genome comparison predicts 100–120 miRNA-encoding genes in Caenorhabditis and Drosophila and approximately 250 in mouse and human (Ambros et al. 2003; Grad et al. 2003; Lai et al. 2003; Lim et al. 2003a, 2003b).”
The Genome Sequence of Caenorhabditis briggsae: A Platform for Comparative Genomics (2003, background): “The microRNA Registry (version 1.4; http://www.sanger. ac.uk/Software/Rfam/mirna/) contains 105 C. elegans microRNA (miRNA) sequences reported by several groups (Lau et al. 2001; Lee and Ambros 2001; Ambros et al. 2003; Grad et al. 2003; Lim et al. 2003).”
Novel and Stress-Regulated MicroRNAs and Other Small RNAs from Arabidopsis (2004, background): “The total number of miRNAs in each organism is unknown but is estimated to represent;1%of the number of coding genes (Grad et al., 2003; Lai et al., 2003; Lim et al., 2003; Bartel, 2004).”
Prediction and validation of microRNAs and their targets (2005, unknown): “Grad et al. [ 20 ] used a similar approach to detect and validate 14 microRNAs in C. elegans.”
Bioinformatic discovery of microRNA precursors from human ESTs and introns (2006, background): “[7], to predict hairpins from raw sequence data.”
Microarray analysis of microRNA expression in the developing mammalian brain (2004, unknown): “elegans, plants, Drosophila melanogaster and mammals [6-18].”
The small RNA profile during Drosophila melanogaster development. (2003, background): “…of noncoding RNAs that are found in plants1150 St. Nicholas Avenue and animals (Ambros et al., 2003b; Dostie et al., 2003;New York, New York 10032 Grad et al., 2003; Lagos-Quintana et al., 2001, 2002, 2003; Lau et al., 2001; Lee and Ambros, 2001; Lee et al., 1993; Lim et al., 2003a, 2003b; Llave…”
Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing. (2004, background): “…2001, 2002, 2003; Lau et al. 2001; Lee and Ambros 2001; Mourelatos et al. 2002; Ambros et al. 2003; Aravin et al. 2003; Brennecke et al. 2003; Dostie et al. 2003; Grad et al. 2003; Houbaviy et al. 2003; Lai et al. 2003; Lim et al. 2003a,b) that encode transcripts that contain short dsRNA hairpins.”
Computational identification of Drosophila microRNA genes (2003, background): “In combination with other concurrent genomic analyses [31-34], it is likely that most miRNAs in completed animal genomes have now been identified.”
Computational identification of plant microRNAs and their targets, including a stress-induced miRNA. (2004, background): “We devel- are characteristic of metazoan miRNA hairpin precuroped comparative genomic approaches to systemati- sors (Ambros et al., 2003b; Grad et al., 2003; Lai et al., cally identify both miRNAs and their targets that are 2003; Lim et al., 2003a, 2003b).”
The functions of animal microRNAs (2004, background): “The lsy-6 miRNA was not detected by cDNA cloning, and had not emerged from computational predictions of worm miRNA”
A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses. (2006, methodology): “However, the majority of these approaches use evolutionary conservation as a preliminary filter to limit the number of candidate miRNAs called by the program (Grad et al. 2003; Lai et al. 2003; Lim et al. 2003a,b; Berezikov et al. 2005).”
Human embryonic stem cells express a unique set of microRNAs. (2004, background): “More than 300 miRNAs have been reported in diverse eukaryotic organisms so far (Aravin et al., 2003; Dostie et al., 2003; Grad et al., 2003; Lagos-Quintana et al., 2001, 2002, 2003; Lai et al., 2003; Lau et al., 2001; Lee and Ambros, 2001; Lee et al., 1993; Lim et al., 2003b; Llave et al., 2002a;…”