Developmental cell death: morphological diversity and multiple mechanisms

By P. Clarke. Anatomy and Embryology, 2004

1,223 citations recorded by the source corpus.

Subfields: Endocrinology, Epidemiology, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/b027a00707f352dda81303e29b35293680239317

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Citations in the corpus

Ferroptosis, a new form of cell death, and its relationships with tumourous diseases (2016, background): “Clarke named type III PCD ‘necrosis’ [32], which is a passive form of cell death.”
Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease (2005, background): “Although macroautophagy appears to be neuroprotective in these settings, sustained overactivity during embryonic development (Clarke, 1990), response to ER stress, exposure to toxins (Kanzawa et al., 2004), or dysfunction of the autophagic pathway in pathological states mediate a…”
Methods for monitoring autophagy. (2004, background): “In addition, autophagy may be involved in a certain type of cell death ( Clarke, 1990) and human diseases such as neurodegener-”
Self-eating and self-killing: crosstalk between autophagy and apoptosis (2007, background): “Indeed, during extensive autophagy, the volume that is occupied by autophagic vacuoles and dense bodies may be roughly equal to, or greater than, that of 'free' cytosol and organelle”
Autophagy: dual roles in life and death? (2005, background): “Three forms of cell death have been defined in dying cells of developing animals on the basis of morphology, location and dependency on lysosome”
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 (2014, background): “Soon thereafter, the first ‘formal’ classification of cell death differentiated between: (1) type I cell death (apoptosis), manifesting with the morphologic features described above; (2) type II cell death (autophagy), featuring an extensive vacuolization of the cytoplasm; and (3) type III cell deat”
Cell death in the nervous system (2006, background): “Although PCD has often been equated with apoptosis, non-apoptotic forms also exis”
Apoptosis, Pyroptosis, and Necrosis: Mechanistic Description of Dead and Dying Eukaryotic Cells (2005, background): “death, autophagy or type II cell death, features degradation of cellular components within the dying cell in autophagic vacuoles (16).”
Morphological and Biochemical Aspects of Apoptosis, Oncosis and Necrosis (2002, methodology): “The word chromatolysis was used later on by Gräper (1914) as an opposite to mitosis for describing cell elimination in the course of which cell debris is phagocyted by neighbouring epithelial cells.”
Lysosomal membrane permeabilization and cell death (2018, background): “The role of lysosomes in programmed cell death was first acknowledged over 50 years ago, when the first attempts to define and classify different types of cell death were made.(3,68) These initial studies focused on embryonic and perinatal development, and for many years, the definition of cell deat”
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. (2003, background): “during embryogenesis (Clarke, 1990) and pathogenesis (Li-”
Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death. (2007, background): “Autophagic cell death is characterized by an abundance of autophagosomes and autolysosomes in the dying cell and differs from apoptotic cell death in that dying cells are degraded by their own lysosomal enzymes, rather than by phagocytosis [13].”
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. (2008, background): “Interestingly, cell death with necrotic features, termed ‘‘type III cell death,’’ has been described to occur during normal development of the nervous system (Clarke, 1990).”
Autophagy gene-dependent clearance of apoptotic cells during embryonic development. (2007, background): “…in other developmental settings where apoptosis and autophagy are known to be active simultaneously, such as salivary gland regression in Drosophila (Baehrecke, 2003), as well as during developmental events characterized primarily by ‘‘autophagic PCD’’ (Clarke, 1990; Lockshin and Zakeri, 2004).”
Autosis and autophagic cell death: the dark side of autophagy (2014, background): “Historically, three types of cell death have been identified based on morphological criteria, including Type I (apoptosis), Type II (autophagic cell death), and Type III (necrosis).(1,2) Autophagic cell death was originally defined as a type of cell death accompanied by large-scale autophagic vacuol”