Targeted gene expression in Drosophila dopaminergic cells using regulatory sequences from tyrosine hydroxylase.

By Florence Friggi-Grelin, Hélène Coulom, Margaret Meller, Delphine Gomez, J. Hirsh, S. Birman. 2003

528 citations recorded by the source corpus.

Subfields: Cell Biology, Cellular and Molecular Neuroscience, Molecular Biology

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Citations in the corpus

Coordinated and Compartmentalized Neuromodulation Shapes Sensory Processing in Drosophila (2015, neutral): “, 1996); TH-Gal4 (Friggi-Grelin et al., 2003); DDC-Gal4 (Li et al.”
The neuronal architecture of the mushroom body provides a logic for associative learning (2014, methodology): “Promoter regions corresponding to the following GAL4 constructs were amplified by PCR: TH-GAL4 (Friggi-Grelin et al., 2003), DdcGAL4 (Li et al., 2000), HL9-GAL4 (Claridge-Chang et al., 2009), and Tdc2-GAL4 (Cole et al., 2005).”
Dopamine Is Required for Learning and Forgetting in Drosophila (2012, neutral): “Gal4 drivers used in this study include TH-gal4 (Friggi-Grelin et al., 2003), c061-gal4 (Krashes et al.”
WRITING MEMORIES WITH LIGHT-ADDRESSABLE REINFORCEMENT CIRCUITRY (2009, background): “and Miesenböck, 2005) were crossed with balanced driver lines TH-GAL4 (Friggi-Grelin et al., 2003) or HL9-GAL4 to yield UAS-P2X2/CyO ; GAL4driver/TMSb males.”
Shared mushroom body circuits underlie visual and olfactory memories in Drosophila (2014, unknown): “, 2007), UAS-mCD8::GFP (Lee and Luo, 1999) or WT-females and males of genotypes TH-GAL4 (Friggi-Grelin et al., 2003), DDC-GAL4 (Li et al.”
Neuronal assemblies of the Drosophila mushroom body (2008, methodology): “Drosophila strains We used GAL4 enhancer-trap strains 201y (Yang et al., 1995), GH146 (Stocker et al., 1997), MB247 (Schulz et al., 1996; Zars et al., 2000), OK107 (Connolly et al., 1996), and TH-GAL4 (Friggi-Grelin et al., 2003) and the MZ and NP series of the GAL4 enhancer-trap lines (Ito et al., ”
Sleep facilitates memory by blocking dopamine neuron mediated forgetting (2015, unknown): “Birman (Friggi-Grelin et al., 2003).”
Drosophila Learn Opposing Components of a Compound Food Stimulus (2014, methodology): “We expressed UAS-GCaMP3 [26] in dopaminergic neurons with TH-GAL4 [27] and imaged DEET-evoked changes in fluorescence in the dopaminergic neuron processes on the mushroom body (Figure 2I).”
Converging circuits mediate temperature and shock aversive olfactory conditioning in Drosophila. (2014, unknown): “UAS- GCaMP3 [50]; UAS-TNT [21]; TH-GAL4 [26]; DDC-GAL4 [27]; TrH-GAL4 [28]; UAS-CD4::spGFP1-10 and LexAop-CD4::spGFP11 [51]; UAS-syt::GFP and UAS-mCD8::GFP from the Bloomington stock center; TH-C0-GAL4, TH-D0-GAL4, and TH-F3-GAL4 [31]; and LexAop-mCD8::GFP and TH-LexA, generated in G.”
Dynamics of learning-related cAMP signaling and stimulus integration in the Drosophila olfactory pathway. (2009, unknown): “This pattern is reminiscent of the distribution of dopaminergic innervation in the mushroom body (Friggi-Grelin et al., 2003; Mao and Davis, 2009), the distribution of dopaminergic receptors (Han et al.”
Light-induced activation of distinct modulatory neurons triggers appetitive or aversive learning in Drosophila larvae. (2006, unknown): “From the obtained transgenic lines, one with a single P element insertion on the second chromosome was used for combination with Gal4 lines carrying the P element on the third chromosome (TH-Gal4 [9], D42-Gal4 [10], elavGal4 [7]).”
Eight Different Types of Dopaminergic Neurons Innervate the Drosophila Mushroom Body Neuropil: Anatomical and Physiological Heterogeneity (2009, unknown): “The tyrosine hydroxylase GAL4 line TH-GAL4 (Friggi-Grelin et al., 2003; kindly provided by S. Birman) was used to drive UAS-mCD8:: GFP, UAS-syt.eGFP or UAS-GFP::LacZ.nls for immunohistochemistry experiments.”
Punishment prediction by dopaminergic neurons in Drosophila. (2005, unknown): “1-82 [24] and TH-Gal4 [23] with flies homozygous for mb247-DsRed.”