Punishment prediction by dopaminergic neurons in Drosophila.

By T. Riemensperger, T. Völler, Patrick Stock, E. Buchner, André Fiala. 2005

349 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Ecology, Evolution, Behavior and Systematics, Genetics

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Citations in the corpus

Dopaminergic neurons write and update memories with cell-type-specific rules (2016, background): “Punitive or rewarding stimuli such as electric shock, heat, cold, bitter taste and sugar generally activate a complex pattern of DANs (Riemensperger et al., 2005; Mao and Davis, 2009; ; Liu et al., 2012; Tomchik, 2013; Galili et al., 2014; Das et al., 2014; Kirkhart and Scott, 2015).”
Coordinated and Compartmentalized Neuromodulation Shapes Sensory Processing in Drosophila (2015, neutral): “HMC02893, generated by the TRiP at Harvard Medical School (NIH/NIGMS R01-GM084947)) (Bloomington Drosophila Stock Center); MB247-DsRed (Riemensperger et al., 2005) (gift from Andre Fiala, University of Göttingen); MB247-LexA (Pitman et al.”
The neuronal architecture of the mushroom body provides a logic for associative learning (2014, background): “Different populations of DANs are activated by USs of different valence; see Figure 1A of the accompanying paper (Aso et al., 2014) for summary (Riemensperger et al., 2005; Mao and Davis, 2009; Liu et al., 2012; Das et al., 2014).”
WRITING MEMORIES WITH LIGHT-ADDRESSABLE REINFORCEMENT CIRCUITRY (2009, background): “, 2008); KCs expressed mb247-DsRed (Riemensperger et al., 2005).”
Light-induced activation of distinct modulatory neurons triggers appetitive or aversive learning in Drosophila larvae. (2006, neutral): “In adult Drosophila, dopaminergic neurons respond to a punishing electric shock stimulus [28], and blocking synaptic transmission from dopaminergic neurons during olfactory learning impairs aversive but not appetitive memory formation [3].”
γ neurons mediate dopaminergic input during aversive olfactory memory formation in Drosophila (2012, neutral): “MBs integrate olfactory conditioned stimulus (CS) inputs with neuromodulatory reinforcement (unconditioned stimuli, US) [1, 2], which for aversive learning is thought to rely on dopaminergic (DA) signaling [3–6] to DopR, a D1-like dopamine receptor expressed in MBs [7, 8].”
Event Timing in Associative Learning: From Biochemical Reaction Dynamics to Behavioural Observations (2012, background): “In the Drosophila brain, individual odours activate small, specific groups of Kenyon cells increasing their intracellular Ca concentration [22–24]; whereas shock induces a dopaminergic reinforcement signal, which is also delivered to the Kenyon cells [25–29].”
Eight Different Types of Dopaminergic Neurons Innervate the Drosophila Mushroom Body Neuropil: Anatomical and Physiological Heterogeneity (2009, positive): “Riemensperger et al. (2005) studied the activity using a FRETbased calcium reporter of DA terminals in a region that covers parts of the α lobe, β lobe and γ lobe.”
Reward signal in a recurrent circuit drives appetitive long-term memory formation (2015, positive): “Our results delineated such a feedback circuit, which was predicted by a physiological study in Drosophila (Riemensperger et al., 2005).”
Drosophila α/β Mushroom Body Neurons Form a Branch-Specific, Long-Term Cellular Memory Trace after Spaced Olfactory Conditioning (2006, neutral): “Dopaminergic neurons that innervate the axons of the MB neurons have been reported to form a calcium-based memory trace immediately after conditioning ( Riemensperger et al., 2005 ), and there is an increase in synaptic protein synthesis in regions of the AL 1 day after spaced olfactory conditioning”
A neural circuit mechanism integrating motivational state with memory expression in Drosophila (2009, methodology): “Some DA neurons innervate the MB heel and base of the peduncle (Friggi-Grelin et al., 2003; Riemensperger et al., 2005; Tanaka et al., 2008) (Figure S4).”
Drosophila olfactory memory: single genes to complex neural circuits (2007, background): “DA neurons innervate wide areas of the brain including the mushroom bodie”
Pain-relief learning in flies, rats, and man: basic research and applied perspectives (2014, background): “However, there is a less widely acknowledged type of memory that relates to what happens after the offset of or after escape from such a painful event, at the moment of “relief” (Fig.”
Neuronal assemblies of the Drosophila mushroom body (2008, methodology): “1 (Fiala et al., 2002), respectively, were crossed with the mb247-DsRed strain (Riemensperger et al., 2005), which was used as a landmark for the MB like UAS-GFP S65T (T10).”