Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion.
By Erik Lubberts, M. Koenders, Birgitte Oppers-Walgreen, L. V. D. van den Bersselaar, C. J. C. Coenen-de Roo, L. Joosten, W. van den Berg. Arthritis & Rheumatism, 2004
753 citations recorded by the source corpus.
Subfields: Immunology, Rheumatology
View Paper: https://www.semanticscholar.org/paper/abe890dace1a3ed1aeed2335caa435c60bf8d236
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Citations in the corpus
- Interleukin 27 negatively regulates the development of interleukin 17–producing T helper cells during chronic inflammation of the central nervous system (2006, background): “IL-23-induced activation of STAT3 has been linked to the promotion of IL-17 production by CD4 + T cell”
- Human inflammatory dendritic cells induce Th17 cell differentiation. (2013, background): “Preclinical studies showed that blocking IL-17 with neutralizing antibodies suppresses collagen-induced arthritis (Lubberts et al., 2004) or ameliorates symptoms in experimental autoimmune encephalomyelitis (Hofstetter et al., 2005).”
- IL-23 drives a pathogenic T cell population that induces autoimmune inflammation (2005, background): “Daniel J. Cua: daniel.cua@dnax.org Abbreviations used: CIA, collagen-induced arthritis; CNS, central nervous system; DLN, draining LN; EAE, experimental autoimmune encephalomyelitis; MOG, myelin-oligodendrocyte glycoprotein peptide; PLP, proteolipid protein peptide.”
- The biological functions of T helper 17 cell effector cytokines in inflammation. (2008, positive): “Also, treatment with IL-17A antibodies after the onset of experimental, collagen-induced arthritis decreases joint damage and histologic destruction of cartilage and bone, and it reduces IL-6 in mouse serum as well (Lubberts et al., 2004).”