Ghrelin: structure and function.

By M. Kojima, K. Kangawa. Physiological Reviews, 2005

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Insulin resistance: Review of the underlying molecular mechanisms (2018, background): “…the “hunger hormone,” is a polypeptide released from the gastrointestinal tract that regulates growth hormone function and, in addition, modulates appetite and energy expenditure by acting on the hypothalamic arcuate nucleus and therefore impacts insulin sensitivity (Kojima & Kangawa, 2005).”
Ghrelin octanoylation mediated by an orphan lipid transferase (2008, background): “These observations are consistent with the identification of octanoylated forms of ghrelin peptides across vertebrates, including lower vertebrates such as zebrafish (3, 5).”
Gut hormones and the regulation of energy homeostasis (2006, background): “This acylation is necessary for ghrelin to bind to the GHS-R and to cross the blood–brain barrie”
Towards Fish Lipid Nutrigenomics: Current State and Prospects for Fin-Fish Aquaculture (2008, methodology): “This functional genomics approach was further used to investigate the physiological function of ghrelin and its receptor, called the GH secretogogue receptor or the ghrelin receptor (Kojima and Kangawa, 2005).”
Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. (2008, neutral): “(Date et al., 2000; Kojima and Kangawa, 2005).”