The terminology issue for myeloid-derived suppressor cells.
By Dmitry I. Gabrilovich, Vincenzo Bronte, Shu-hsia Chen, M. P. Colombo, Augusto C Ochoa, S. Ostrand-Rosenberg, Hans Schreiber. Cancer Research, 2007
809 citations recorded by the source corpus.
Subfields: Immunology
View Paper: https://www.semanticscholar.org/paper/a0b80f3f86a06dd81b074cafda9190b6a463414e
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In Immunology
- D. Gabrilovich
- A. Mantovani
- J. Pollard
- V. Bronte
- S. Ostrand-Rosenberg
- P. Allavena
- J. Joyce
- Zena Werb
Citations in the corpus
- Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives (2008, background): “Recently, a panel of leading investigators in the field agreed to use the common term ‘myeloid derived suppressor cells’ (MDSCs) to name these arginase I-producing cells (99).”
- Tumor‐induced tolerance and immune suppression by myeloid derived suppressor cells (2008, positive): “The acronym MDSCs, which reflects the myeloid origin (thus including both mature and immature/precursor phenotypes) and the immunosuppressive functions (18), was recently accepted by some investigators to replace the previous terms of ‘myeloid suppressor cells (MSCs)’ or ‘immature myeloid cells (iMC”
- Adipose Tissue in Obesity-Related Inflammation and Insulin Resistance: Cells, Cytokines, and Chemokines (2013, neutral): “Later on, these cells were defined as “myeloid-derived suppressor cells” (MDSC) because of their myeloid origin and their ability to suppress immune responses [106].”
- IL-6 in inflammation, autoimmunity and cancer (2020, background): “The requirement for human naive T cells in T h 17 cell differentiation differs from that of mice, since human T cells in the presence of IL-1 β with IL-6 or IL-23 can differentiate to T h 17 cells without TGF β (169, 170).”
- Tumor‐associated macrophages (TAM) as major players of the cancer‐related inflammation (2009, background): “However, as these cells share properties and gene expression profiles with M2-polarized TAM [34, 61] it is likely that, by nature, they skew toward the M2 orientation.”
- Microenvironmental regulation of metastasis (2009, background): “Another BMDC type, which may share a common progenitor with TAMs, is the MDS”
- Tumor-derived granulocyte-macrophage colony stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer (2012, methodology): “Furthermore, normal pancreatic ductal cells also secreted VEGF (albeit somewhat less so than PDA cells) yet Gr-1 + CD11b + cells did not accumulate around normal ducts in vivo and conditioned media from normal ductal cells failed to support proliferation of c-kit + splenocytes into MDSC.”
- The role of myeloid cells in the promotion of tumour angiogenesis (2008, background): “Indeed, it is their ability to potently suppress the anti-tumour functions of T and natural killer (NK) cells, along with DC maturation, that currently provides the most effective way of identifying MDS”
- Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy (2008, positive): “In addition, 13% co-expressed CD11b and Gr1 (Ly-6G), a marker for neutrophils and MDSCs (Mordue and Sibley, 2003; Gabrilovich et al., 2007) (Fig.”
- Cancer to bone: a fatal attraction (2011, neutral): “Myeloid-derived suppressor cells (MDSCs) are a subpopulation of immature myeloid cells that are characterized by GR1 expression and by the αMβ2 (CD11b) integrin adhesion marke”