MAPK signal specificity: the right place at the right time.

By Leon O. Murphy, J. Blenis. TIBS -Trends in Biochemical Sciences. Regular ed, 2006

740 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/9bdcff22eef4f4918724465e22029e52101ec2bd

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In Molecular Biology

Citations in the corpus

Understanding MAPK Signaling Pathways in Apoptosis (2020, background): “However, sustained activation of ERK signaling is not only involved in apoptosis but also in cell cycle progression, cellular transformation, and differentiation [97].”
Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases (2007, background): “…internalization of cell surface receptors, the association of MAPK signalling components with scaffold proteins, and the balance between kinase activation and negative regulatory controls such as protein phosphatases (Volmat and Pouyssegur, 2001; Morrison and Davis, 2003; Murphy and Blenis, 2006).”
The MEK/ERK cascade: from signaling specificity to diverse functions. (2007, background): “The most prominent example for this mechanism is the transcription factor c-Fos, a known target of the ERK cascade [86] that induces both its expression and stabilization upon stimulation.”
Molecular mechanisms of mTOR-mediated translational control (2009, background): “The Ras–ERK pathway has an established role in regulating transcriptio”
Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways (2017, background): “IEG products include c-FOS and c-MYC, which induce late-response genes, to promote various phenotypes associated with ERK signaling [211].”
MAP kinase signalling pathways in cancer (2007, background): “In part at least, these properties may be linked to temporal differences in the strength and localization of ERK within the cell (Murphy and Blenis, 2006).”