TNF/TNFR family members in costimulation of T cell responses.

By T. Watts. Annual Review of Immunology, 2005

1,494 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/9a45d22c9915502efc86daa16b8b3a012cc3baf5

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Citations in the corpus

Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production. (2007, background): “Some molecules up-regulated upon TCR stimulation, such as CD25 and GITR, serve to enhance T cell activation by increasing sensitivity to cytokines or chemokines, or providing co-stimulatory signals (33, 34 ).”
Shaping and reshaping CD8+ T-cell memory (2008, background): “Inflammation and memory T-cell differentiation Early experiments revealed that not only peptide–MHC complexes (signal 1), but also co-stimulatory signals (signal 2) were required to activate naive T cell”
Immunostimulatory monoclonal antibodies for cancer therapy (2007, neutral): “or the tumour-necrosis factor receptor (TNFR) superfamilie”
CD28− T cells: their role in the age-associated decline of immune function (2009, background): “CD27-CD70 is another co-stimulatory receptorligand pair involved in T cell activation [57].”
CD27 Dissects Mature NK Cells into Two Subsets with Distinct Responsiveness and Migratory Capacity1 (2006, background): “In particular, interactions between a variety of TNFR superfamily and TNF superfamily members have been shown to play a key role in promoting lymphocyte survival, and the expression level of TNF receptor super family correlates with the maturity of T cells and B cells (30).”
CD8+ T Cells: Foot Soldiers of the Immune System (2011, neutral): “Many members of the tumor necrosis factor receptor (TNFR) family such as 4-1BB, CD27, and OX-40 deliver important costimulatory signals to CD8 + T cells (Watts, 2005).”
Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cells. (2008, background): “Looking at the cell surface, LCs express more 4-1BBL, an activator of CD8+ T cells (Watts, 2005), but anti-4-1BB-L blocked T cell priming by both subsets (data not shown).”
Signals required for programming effector and memory development by CD8+ T cells (2006, background): “We found that the aAPCs were effective in stimulating clonal expansion and development of cytolytic activity by memory cells but were ineffective in stimulating responses by naı̈ve cells, even at very high antigen or B7 ligand surface densities.”
Impact of genetic polymorphisms on human immune cell gene expression (2018, neutral): “…to influence T cell function, such as, the immune checkpoint molecule PDCD1 (PD-1) (Keir et al., 2008), the co-stimulatory molecule TNFRSF9 (4–1BB) (Watts, 2005), the co-inhibitory molecule CD59 (Sivasankar et al., 2009) and SGK1 (Wu et al., 2013), a kinase that regulates differentiation of T H 17…”
Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection. (2007, background): “Costimulatory signals (signal 2) from receptors such as CD28, CD40, 41BB, CD27, ICOS, and OX40 clearly impact the size of the antiviral effector and memory T cell populations, with some notable differences in their effects on CD4+ versus CD8+ T cells (Greenwald et al., 2005; Watts, 2005).”