Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency.

By G. López-Lluch, Nicole D. Hunt, Bruce A. Jones, Min Zhu, H. Jamieson, S. Hilmer, María V Cascajo, Joanne S. Allard, D. Ingram, Plácido Navas and 1 more. Proceedings of the National Academy of Sciences of the United States of America, 2006

690 citations recorded by the source corpus.

Subfields: Geriatrics and Gerontology, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/9816ae6dcc70059700b11dadf15e4c2c32d44596

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Citations in the corpus

Mitochondrial Dysfunction in Diabetes: From Molecular Mechanisms to Functional Significance and Therapeutic Opportunities (2010, positive): “How this is re-lated to mitochondrial function is not clear, but evidence suggests that calorie restriction favors mitochondrial biogenesis, oxygen use and ATP formation, and expression of SIRT1, which activates PGC1-a (121, 203).”
The mitochondrial energy transduction system and the aging process. (2007, background): “Recently, it was reported that caloric restriction induces mitochondrial biogenesis and increases bioenergetic efficiency (97).”
The role of mitochondria in aging. (2013, neutral): “115, 116, and Figure 3).”
Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome. (2013, background): “Mitochondrial Integrity CR is reported to enhance mitochondrial proliferation (Civitarese et al., 2007; López-Lluch et al., 2006).”
Therapeutic potential of resveratrol: the in vivo evidence (2006, result): “, which is consistent with observations in calorie-restricted animal”
Extending life span by increasing oxidative stress. (2011, background): “Furthermore, CR promotes mitochondria biogenesis and OxPhos in rodents as well as enhancement of respiratory capacity in mammalian cells [114,115].”
How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis). (2010, background): “Additionally, it has been suggested that mass-specific energy expenditure in CR rats is higher than expected (Selman et al., 2005) and that cultured mammalian cells induce their respiratory capacity in states of CR (Lopez-Lluch et al., 2006).”
Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals? (2007, background): “In cells that are grown in serum from calorie-restricted rats, mitochondrial biogenesis is increased and bioenergetics efficiency is improved while ROS generation is reduce”