How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis).

By Michael Ristow, K. Zarse. Experimental Gerontology, 2010

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View Paper: https://www.semanticscholar.org/paper/7df2a59d94d589edeabd2cdccb331162a55e560f

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Citations in the corpus

Mitochondrial ROS signaling in organismal homeostasis. (2015, background): “They and others have subsequently found that increased mtROS is a common downstream event in many conserved longevity-promoting interventions, which has led to the concept of ‘‘mitohormesis’’ (Ristow and Zarse, 2010; Yun and Finkel, 2014).”
The emerging role of reactive oxygen and nitrogen species in redox biology and some implications for plasma applications to medicine and biology (2012, background): “With respect to the effects of ROS on organism lifetime, there is some evidence now that ROS, acting through mitochondrial metabolism, are sometimes associated with increased lifespan, as described by Ristow and Zarse [15], Ristoe and Schmeisser [16] and Hekimi et al [17].”
Replicative and Chronological Aging in Saccharomyces cerevisiae (2012, neutral): “In addition, mitochondrial (or other) hormetic effects on stress-resistance pathways may also help explain why some aging studies do not document a positive correlation between ROS levels and macromolecular damage (Ristow and Zarse, 2010).”
Signal transduction by reactive oxygen species (2011, background): “, 2007) and are generally ascribed to the concept of mitochondrial hormesis (Ristow and Zarse, 2010), the biological equivalent of Fredrick Nietzsche dictum, “what won’t kill you, will make you strong.”
Autophagy and aging. (2011, background): “If hormesis determined the pace of aging and death, as has been postulated (Le Bourg, 2009), and if autophagy were one of the effector mechanisms of hormesis, for instance as a cleansing mechanism of damaged organelles (Ristow and Zarse, 2010), then improved hormesis might constitute one of the link”