Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals?
By M. Giorgio, M. Trinei, E. Migliaccio, Pier Giuseppe Pelicci. Nature reviews. Molecular cell biology, 2007
1,438 citations recorded by the source corpus.
View Paper: https://www.semanticscholar.org/paper/13a793786b17a34e84101de4552f2c24608ea590
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Citations in the corpus
- From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis. (2010, background): “Formation of ROS is an inescapable consequence of life in an oxygen-rich environment and occurs primarily in the mitochondria from the escape of electrons passing through the electron transport chain during aerobic metabolism—the process that is fueled by nutrients such as glucose and is responsible”
- Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements (2019, background): “Indeed, hydrogen peroxide (H2O2) is one of the most important among the ROS group which is a direct and potent inducer of apoptosis [103].”
- Disorders of bone remodeling. (2011, background): “There is an age-related increase in ROS levels that arises from age-related increases in ROS production and/or a decrease in antioxidants (89, 90).”
- Reactive Oxygen Species Signaling and Oxidative Stress: Transcriptional Regulation and Evolution (2024, background): “…damaging effects, recent research has unveiled the dual role of ROS as vital signaling molecules engaged in regulating numerous biological processes [4]. conserved in various life forms, and it becomes toxic at concentrations above 0.5 × 10 − 4 M, at which it induces cell apoptosis [41].”
- Oxidative stress in cyanobacteria. (2009, background): “oxygen diffuses passively into the cell and is reduced to superoxide anion and H2O2 via the oxidation of flavoproteins, such as the NADH dehydrogenase II (NdhII) in Escherichia coli (for reviews, see Imlay, 2003; Giorgio et al., 2007).”