Arterial aging: is it an immutable cardiovascular risk factor?

By S. Najjar, A. Scuteri, E. Lakatta. HYPERTENSION, 2005

677 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Immunology

View Paper: https://www.semanticscholar.org/paper/9734fb9265b5a902b4c4a84463b04bfe40f6cfcd

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cardiology and Cardiovascular Medicine

1. Hannah J. Zhang
2. Gary F. Mitchell
3. K. Kregel

In Immunology

1. J. Campisi
2. M. Demaria
3. Adam Freund
4. C. Patil
5. J. Kirkland
6. Jesús Gil
7. Y. Fouad
8. C. Aanei

Citations in the corpus

• Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: a consensus statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force. Endorsed by the Society for Vascular Medicine. (2008, background): “It represents subclinical vascular disease, the pathophysiologic substrate that explains why CIMT is a risk factor and a marker of CVD risk.(56,57)”
• Renin‐angiotensin system revisited (2008, background): “Arterial components of the Ang II-signalling cascade increase with ageing [70] .”
• The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression (2010, background): “External mitogenic signals, for example growth-related oncogene alpha (GROα) secretion by tumor cells in close proximity to normal cells (32) or circulating angiotensin II (33, 34), have also been shown to induce cellular senescence.”
• An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations. (2007, background): “While it is unclear whether longerterm antioxidant treatments might prove effective in dealing with aging and conditions, such as vascular aging, provocative results from acute-treatment studies suggest that the vasculature should be viewed as a key target for therapeutic intervention (133, 180, 239”
• Arterial stiffness, pressure and flow pulsatility and brain structure and function: the Age, Gene/Environment Susceptibility--Reykjavik study. (2011, background): “Increased CFPWV is associated with collagen deposition and fibrosis in the aortic wall (Najjar et al., 2005).”
• Senescent cells as a source of inflammatory factors for tumor progression (2010, background): “External mitogenic signals, for example growth-related oncogene alpha (GROα) secretion by tumor cells in close to normal cells [36] or circulating angiotensin II [37, 38], have also been shown to induce cellular senescence.”