Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity.

By Huck-Hui Ng, F. Robert, Richard A. Young, Kevin Struhl. Molecules and Cells, 2003

1,187 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/93b29d7c91997131bd620ad39a7d14ddfdde97bc

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Citations in the corpus

A chromatin landmark and transcription initiation at most promoters in human cells. (2007, background): “Previous studies have emphasized that nucleosomes with histone H3K4me3 are associated with actively transcribed genes in various eukaryotes (Bernstein et al., 2002; Santos-Rosa et al., 2002; Ng et al., 2003; Schneider et al., 2004; Schubeler et al., 2004; Pokholok et al., 2005).”
Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation (2009, background): “The presence of H3K4me3 at inactive genes has been proposed to be a memory for past transcriptional activity based on studies performed in yeast (Ng et al., 2003).”
A global map of p53 transcription-factor binding sites in the human genome. (2006, methodology): “For all ChIP experiments, quantitative PCR analyses were performed in real time using ABI PRISM 7900 Sequence Detection System and SYBR Green master mix as described (Ng et al., 2003).”
Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells. (2007, background): “regions of actively transcribed genes ( Ng et al., 2003; Santos-Rosa et al., 2002; Schneider et al., 2004), we first examined the correlation between these 17,167 PETdefined H3K4me3 loci and transcription start sites (TSSs) of known genes.”
The RNA polymerase II CTD coordinates transcription and RNA processing. (2012, background): “H3K4 and H3K36 methylation patterns similar to those in yeast have been observed in higher eukaryotes (Bannister et al. 2005; Barski et al. 2007; Edmunds et al. 2008).”
Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription (2013, background): “Previous studies have shown that members of the Mll family of HMTs are able to associate with the C-terminal domain (CTD) of RNAPII, in some cases dependent on phosphorylation of CTD serine 2 (Hughes et al., 2004; Krogan et al., 2003; MacConaill et al., 2006; Milne et al., 2005; Ng et al., 2003; Ran”
Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions (2006, neutral): “The spatial distribution of trimethylated H3-K4 at the Dbp gene is in keeping with the proposal that Set1, the responsible methyltransferase, travels with the elongating RNA polymerase II complex some distance along a gen”
The interplay of histone modifications – writers that read (2015, neutral): “Work in yeast shows that SET1 associates with the PAF complex and the Ser5-phosphorylated initiating form of Pol II and is co-transcriptionally deposited [18] (Fig 3).”
Genomic maps and comparative analysis of histone modifications in human and mouse. (2005, background): “This functional conservation supports the biologiactively transcribed regions in yeast (Bernstein et al., cal importance of these sites. 2002; Ng et al., 2003; Santos-Rosa et al., 2002).”
Methylation of Histone H3 by Set2 in Saccharomyces cerevisiae Is Linked to Transcriptional Elongation by RNA Polymerase II (2003, background): “These results suggested that the function of Set2 is similar in some way to the functioning of COMPASS and the Set3 complex.”
Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. (2005, background): “…residues may be mono-, di-, or trimeth- s aylated in vivo, the trimethyl H3 K4 is preferentially and strongly associated with the transcribed regions of l Hactive genes from yeast to higher eukaryotes (Krogan et al., 2002; Ng et al., 2003; Santos-Rosa et al., 2002; o tSchneider et al., 2004).”
Histone variant H2A.Z marks the 5' ends of both active and inactive genes in euchromatin. (2005, methodology): “Z (Meneghini et al., 2003) and three histone modifications: acetylation on lysine 16 of the H4 tail (Kimura et al., 2002; Suka et al., 2002) and methylation of lysines 4 and 79 of H3 (Ng et al., 2003a; Santos-Rosa et al., 2004; van Leeuwen et al., 2002).”
The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote. (2004, background): “Furthermore, studies in mammalian cell lines showed that H3-di-meK79 is hypermethylated in euchromatin (Ng et al. 2003a).”