A chromatin landmark and transcription initiation at most promoters in human cells.

By M. Guenther, S. Levine, Laurie A. Boyer, R. Jaenisch, Richard A. Young. Cell, 2007

2,054 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/0439ba2f434ce40eb893bec358c0e925a2e5304c

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Citations in the corpus

Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. (2008, background): “A similar result is obtained for H3K4 trimethylation, which colocalizes with H3K4 dimethylation at almost all promoters (Figure S7 and data not shown). gene activation, even in the absence of transcription (Guenther et al., 2007; Pan et al., 2007; Zhao et al., 2007).”
Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. (2009, background): “…are consistent with recent observations that H3K4me3 associates extensively with proximal promoters in human T cells, as well as human and murine embryonic stem cells (Barski et al., 2007; Fouse et al., 2008; Guenther et al., 2007; Mikkelsen et al., 2007; Pan et al., 2007; Zhao et al., 2007).”
Linking DNA methylation and histone modification: patterns and paradigms (2009, background): “H3K4 methylation might be directed by sequence-directed binding of RNA polymerase II, which recruits specific H3K4 methyltransferase”
A unique chromatin signature uncovers early developmental enhancers in humans (2010, neutral): “All (36,693) Class I (4,381) Class II (1,795) P<2.”
Molecular mechanisms of long noncoding RNAs (2011, background): “Archetype II: Decoys The pervasive transcription of enhancers and promoters (Guenther et al., 2007) hints at a central role for lncRNAs in regulating transcription, both positively and negatively.”
How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers (2007, background): “Within this defined region, H3K4me3 is highly correlated with active transcription start site”
The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation (2010, background): “Transcriptional regulation at steps subsequent to PIC assembly is a major regulatory feature, at least in metazoan systems, and has come to attention most dramatically through the discovery of the so-called paused Pol II molecules that can be detected at the majority of transcription units regardles”
An extended transcriptional network for pluripotency of embryonic stem cells. (2008, background): “Previously identified clusters of gene promoters devoid of H3K4me3 and H3K27me3 marks on their promoters in hES cells (Guenther et al., 2007; Zhao et al., 2007) are also not bound by any of nine factors we tested (Figure S7).”