An E3-like factor that promotes SUMO conjugation to the yeast septins.

By Erica S. Johnson, Aseem A. Gupta. Cell, 2001

675 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/90ad79b003af1a306a2d0f2e8a3bce503d033ce4

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

Citations in the corpus

RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO (2002, background): “We also noticed that modification of PCNA by SUMO is mediated by SIZ1, a SUMO ligase of the SIZ/PIAS famil”
SIZ1-Mediated Sumoylation of ICE1 Controls CBF3/DREB1A Expression and Freezing Tolerance in Arabidopsis[W][OA] (2007, background): “Yeast SUMO E3 ligases, Siz1 and 2, facilitate cell division at low temperatures (Johnson and Gupta, 2001).”
Ubiquitin: structures, functions, mechanisms. (2004, neutral): “[23,65]; see also article by Johnson).”
Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation (2003, background): “SUMO modification of PCNA by Ubc9p and the SUMO-specific ligase Siz1”
SUMO and ubiquitin in the nucleus: different functions, similar mechanisms? (2004, background): “RanBP2 and the PIAS proteins interact with the SUMO E2 conjugating enzyme Ubc9 and promote transfer of SUMO from Ubc9 to substrate proteins (Johnson and Gupta 2001; Kahyo et al. 2001; Takahashi et al. 2001; Pichler et al. 2002).”
Modification of proteins by ubiquitin and ubiquitin-like proteins. (2006, background): “Indeed, in many cases, in vitro sumoylation reactions at high concentrations of SUMO E1 and E2 result in the correct targeting of the same lysine that normally is modified in vivo, without addition of a specific E3 (Johnson & Gupta 2001).”
Insights in Post-Translational Modifications: Ubiquitin and SUMO (2022, background): “SUMO E3 activity in vivo and in vitro was observed for first time in 2001, where SIZ1 and SIZ2 SUMO E3s were required for most SUMO conjugation in yeast [101] and PIAS1 acted as a SUMO E3 towards p53 in human cells [102].”
Regulation of JAK–STAT signalling in the immune system (2003, background): “Interestingly, PIAS proteins have been shown to have SUMO E3 ligase activit”