Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation

By Philipp Stelter, H. Ulrich. Nature, 2003

875 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/685a6f88630b9ef0d0ec0b839abd00a9ab599757

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Citations in the corpus

A novel function of DNA polymerase ζ regulated by PCNA (2006, background): “…Organization The EMBO Journal VOL 25 | NO 18 | 2006 4319 113 strains showed a complete deficiency in UV-induced mutagenesis (Figure 4C), reminiscent of the UV-mutability defect caused by the pol30-K164R mutation that prevents ubiquitination of PCNA (Stelter and Ulrich, 2003; Haracska et al, 2004).”
PCNA, the maestro of the replication fork. (2007, positive): “Yeast genetic studies indicated that monoubiquitylated PCNA is linked to the TLS polymerases Polη (Rad30) and Polζ (Rev3/Rev7) (Stelter and Ulrich, 2003), and indeed human Polη was found to interact specifically with monoubiquitylated PCNA (Kannouche et al., 2004; Watanabe et al., 2004) (Figure 3B).”
Ubiquitylation and cell signaling (2005, background): “the same site signals error-free DNA repair (Figure 2C) (Hoege et al, 2002; Stelter and Ulrich, 2003).”
Maintaining genome stability at the replication fork (2010, background): “Rad6- and Rad18-dependent monoubiquitylation promotes TLS in both yeast and mammalian cell”
Loss of DNA Polymerase ζ Causes Chromosomal Instability in Mammalian Cells (2006, background): “i(13) rob(4;14) der(1)t(1;5) dic(17) der(19)ins(3;19) i(13)t(13;14)”
Reading protein modifications with interaction domains (2006, background): “, membrane fusion during organelle reassembly after mitosis and post-replicative DNA repai”
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. (2007, background): “In addition, monoubiquitylation of a number of proteins has been demonstrated to be responsible for protein-protein interactions (GarciaHiguera et al., 2001; Matsushita et al., 2005; Pavri et al., 2006; Stelter and Ulrich, 2003; Taniguchi et al., 2002).”
SUMO and ubiquitin in the nucleus: different functions, similar mechanisms? (2004, background): “SUMO modification of yPCNA has been suggested to increase activity of the translesion DNA polymerase and inhibit a recombination-dependent bypass mechanism during S phase (Stelter and Ulrich 2003; Haracska et al. 2004).”
Ubiquitin and ubiquitin-like proteins as multifunctional signals (2005, background): “cerevisiae , it now seems that all three mechanisms of DNA repair are brought about by the modification of the same residue (K164) in the proliferating cell nuclear antigen (PCNA) DNA-replication processivity facto”