Modification of proteins by ubiquitin and ubiquitin-like proteins.

By Oliver Kerscher, R. Felberbaum, M. Hochstrasser. Annual Review of Cell and Developmental Biology, 2006

1,616 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/8bcecfd4a4dc80af4c95d76f7804f2fa9b19c11d

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In Immunology

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Citations in the corpus

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures. (2008, background): “Of all the genes upregulated by IFN-a/b, ISG15 is one of the most inducible, and yet little is known about its function (reviewed by Kerscher et al., 2006).”
The role of ubiquitination in tumorigenesis and targeted drug discovery (2020, background): “Blocking the neddylation of cullins leads to substrate accumulation.(99,100) Small ubiquitin-related modifier.”
Origin and Function of Ubiquitin-like Protein Conjugation (2009, background): “In a similar manner, distinct but evolutionarily related enzyme cascades catalyse the attachment of ubiquitin-like proteins (UBLs) to proteins or other molecule”
Auxin receptors and plant development: a new signaling paradigm. (2008, background): “RUB modification may be important for the recruitment of the Ub-E2 to the SCF (Kerscher et al. 2006).”
GPS-SUMO: a tool for the prediction of sumoylation sites and SUMO-interaction motifs (2014, background): “Recently, it was reported SUMOs can non-covalently interact with other proteins through targeting specific SIMs, which were also called as SUMO-binding motifs (SBMs) (14–16).”
Atypical ubiquitin chains: new molecular signals (2008, background): “…(SuMO), interferonstimulated gene 15 (iSg15), autophagy 8 (atg8) and neural precursor cell expressed, developmentally downregulated 8 (NEDD8; Kerscher et al, 2006). ubls have a similar structural-fold to ub, but use specific conjugation machineries and are recognized by distinct ubl-binding…”
The role of JAK-STAT signaling pathway and its regulators in the fate of T helper cells (2017, background): “ISGylation (Interferon Stimulated Gene 15): ISG15 is a 17,145 Da ubiquitin like eukaryotic protein, which is induced by type I Interferons, viral infections and lipopolysaccharide encounter [107] and it can modify the function and localization of its target proteins after covalent attachment [108].”
The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition (2010, background): “The SUMO proteins share structural similarities with ubiquitin, and their conjugation to substrates occurs through a related enzymatic cascade involving the sequential action of an E1 activating enzyme, an E2 conjugating enzyme and an E3 protein ligas”
BRK Targets Dok1 for Ubiquitin-Mediated Proteasomal Degradation to Promote Cell Proliferation and Migration (2014, background): “residues in proteins targeted for degradation [55].”