Essential role of brain-derived neurotrophic factor in adult hippocampal function.

By L. Monteggia, M. Barrot, Craig M. Powell, O. Berton, V. Galanis, T. Gemelli, S. Meuth, A. Nagy, R. Greene, E. Nestler. Proceedings of the National Academy of Sciences of the United States of America, 2004

697 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Developmental Neuroscience

View Paper: https://www.semanticscholar.org/paper/9056b129b3a2269da14a27185b1a9b3f7c992905

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Citations in the corpus

Forced swimming test in mice: a review of antidepressant activity (2004, methodology): “2001) or inducible BNDF knock-out (Monteggia et al. 2004).”
The mesolimbic dopamine reward circuit in depression. (2006, background): “…in hippocampus, where its induction by antidepressant treatments seems to be important for their behavioral activity (Duman et al 1997; Monteggia et al 2004; Duman and Monteggia 2006; but see Conti et al 2002, who show that CREB is important for BDNF expression in hippocampus but that…”
BDNF — a key transducer of antidepressant effects (2015, background): “In this context, BDNF has been linked to the mechanism of action of antidepressants (Duman et al., 1997; Ghosh et al., 1994; Monteggia et al., 2004; Duman and Monteggia, 2006).”
Mood and anxiety related phenotypes in mice : characterization using behavioral tests (2009, background): “Moreover, various behavioral, neurochemical and endocrine measures of depression and antidepressant action have been investigated in these mice (14, 23).”
The molecular neurobiology of depression (2008, positive): “Neurotrophins and neurogenesis Volumetric decreases observed in the hippocampus and other forebrain regions in subsets of depressed patients have supported a popular hypothesis for depression involving decrements in neurotrophic factors — neurodevelopmentally expressed growth factors that also re”
Depression: An Evolutionarily Conserved Mechanism to Terminate Separation Distress? A Review of Aminergic, Peptidergic, and Neural Network Perspectives (2009, background): “An additional challenge to noradrenergic-centered points of view on depression has been the recent discovery in one important animal model (Monteggia et al., 2004) that blocking the effect that noradrenergic and serotonergic antidepressants have on the upregulation of BDNF prevents antidepressant…”
Cortical inhibitory neurons and schizophrenia (2005, background): “By contrast, although the expression of BDNF mRNA was decreased by 80% in the prefrontal cortex of mice with a neuron-specific inducible knockout of Bdnf”
Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action (2006, background): “, whereas mice lacking BDNF show impaired antidepressant response”
Stress, Depression, and Neuroplasticity: A Convergence of Mechanisms (2008, background): “…its multiple developmental roles, complicating analysis of its role in learning and memory; but recent studies that have disrupted BDNF only in the adult animal indicate a critical role in information processing and storage (Monteggia et al, 2004; Heldt et al, 2007; reviewed in Pang and Lu, 2004).”
The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity (2010, background): “Conversely, in mice with reduced brain BDNF levels or TrkB signaling, antidepressant drugs fail to produce behavioral responses (Saarelainen et al., 2003; Monteggia et al., 2004).”
The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior (2007, background): “Inducible knockdown of BDNF in the forebrain of adult mice does not influence basal immobility in the FST when compared with wild-type control animals but does block the antidepressant response in the FST (Monteggia et al., 2004, 2007).”
Epigenetic regulation in psychiatric disorders (2007, background): “Chronic ECS upregulates the expression of Bdnf and Creb in the hippocampus, and such upregulation has been shown to mediate antidepressant activity in animal model”