DNA damage checkpoints: from initiation to recovery or adaptation.

By J. Bartek, J. Lukas. Current Opinion in Cell Biology, 2007

829 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/8c548c9e0c774195795b3b9f73a39c30289142ea

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. S. Polo
2. Stephen P. Jackson
3. P. Jeggo
4. Dana Branzei
5. E. White
6. M. Foiani
7. M. Löbrich

In Molecular Biology

1. E. White
2. P. Jeggo
3. Stephen P. Jackson
4. S. Polo
5. Dana Branzei
6. M. Löbrich
7. V. Karantza-Wadsworth
8. Robin Mathew

In Oncology

1. P. Jeggo
2. M. Löbrich
3. S. Polo
4. Stephen P. Jackson
5. Cary A. Moody
6. Dana Branzei
7. E. White
8. M. Foiani

Citations in the corpus

• Role of autophagy in cancer (2007, background): “This is analogous to the mechanism by which defects in DNA repair cause sensitivity to DNA damage, yet the accelerated rate of mutation that results from deficient DNA repair confers an increased incidence of tumour formatio”
• Human papillomavirus oncoproteins: pathways to transformation (2010, background): “Claspin proteolysis is essential for DNA damage checkpoint recover”
• Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. (2011, background): “Resumption of cell cycle progression following DNA repair requires switching off the DDR (Bartek and Lukas 2007), which involves disassembly of DDR foci.”
• Chapter 1. General introduction (2015, neutral): “ATR phosphorylates the Chk1 with the help of the Claspin mediator protein (12).”
• Mitotic catastrophe: a mechanism for avoiding genomic instability (2011, neutral): “This allows the DNA repair machinery time to attempt to recover genome integrit”
• Regulation of DNA repair throughout the cell cycle (2008, background): “The checkpoint-activation network Checkpoints are cellular surveillance and signalling pathways that coordinate DNA repair with chromosome metabolism and cell-cycle transition”
• The impact of a negligent G2/M checkpoint on genomic instability and cancer induction (2007, background): “Recently, it was reported that human tumour cells also show checkpoint adaptation after prolonged incubation following exposure to 6 Gy, and enter mitosis with multiple unrepaired DSB”