Mitotic catastrophe: a mechanism for avoiding genomic instability

By Ilio Vitale, L. Galluzzi, M. Castedo, Guido Kroemer. Nature reviews. Molecular cell biology, 2011

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Neuronal Cell Death. (2018, neutral): ““Mitotic catastrophe” refers to cell death induced by aberrant mitosis (94, 682, 700).”
Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer (2013, background): “Tumor cells undergoing mitotic catastrophe often have checkpoint deficiencies that result in incomplete DNA repair, replicative infidelity and chromosomal desegregation.(103) The”
Molecular mechanisms of cisplatin resistance (2012, background): “…of damage is limited, cisplatin adducts induce an arrest in the S and G2 phases of the cell cycle, a phenomenon that exerts cytoprotective effects by (1) allowing repair mechanisms to re-establish DNA integrity and (2) preventing potentially abortive or abnormal mitoses (Vitale et al., 2011).”
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018, background): “The precise molecular mechanisms through which mitotic alterations are sensed and trigger mitotic catastrophe cascade are unclear, but presumably involve p53 (at least in many cell types) [975].”
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 (2011, background): “executioner mechanism, but an oncosuppressive pathway that precedes and is distinct from, yet operates through, cell death or senescence.(106,108)”