The impact of a negligent G2/M checkpoint on genomic instability and cancer induction

By M. Löbrich, P. Jeggo. Nature Reviews. Cancer, 2007

640 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/0715cb45c17ca834f0e220fd1910541a53aa2866

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In Molecular Biology

1. Christian Staudt
2. G. Iliakis
3. Wenqi Wu
4. A. Kinner

Citations in the corpus

• Strategies to improve radiotherapy with targeted drugs (2011, background): “Cells may be halted in their transition from G1 phase to S phase of the cell cycle, intra-S phase and at the G2/M boundar”
• γ-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin (2008, background): “Amplification of the checkpoint signal may be important for a small number of DSBs that require longer repair times and may help reduce checkpoint evasion in the presence of DNA damage (100,101).”