Regulation of DNA repair throughout the cell cycle

By Dana Branzei, M. Foiani. Nature reviews. Molecular cell biology, 2008

1,260 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Chapter 1. General introduction (2015, positive): “to DSBs, whereas ATR is activated by single-stranded DNA (ssDNA) and stalled replication forks (9).”
Maintaining genome stability at the replication fork (2010, background): “The repair of DSBs is not restricted to S phase and, therefore, an in-depth description of the mechanisms involved is not addressed here, but we invite readers to other review”
Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: tipping the scales of cancer (2008, background): “Notably, β-TrCP has also emerged as a key player in the S and G2 DNA-damage response checkpoin”
Metabolic regulation of hematopoietic stem cells in the hypoxic niche. (2011, background): “DNA double strand breaks (DSBs) that do occur during G0 in HSCs are immediately repaired by nonhomologous end joining, which tends to be more error prone than homologous recombination (Branzei and Foiani, 2008).”
Regulation of homologous recombination in eukaryotes (2010, background): “NHEJ: nonhomologous end joining phosphorylation, ubiquitylation, and sumoylation, have recently been identified (14, 17) (Table 1).”