Neurogenesis in adulthood : a possible role in learning

By E. Gould, P. Tanapat, N. Hastings, T. Shors. 1999

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Citations in the corpus

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? (2010, positive): “Computational models of adult-born DGC function As adult neurogenesis has become more widely appreciated as an important form of hippocampal plasticity, its potential to affect learning and memory has been increasingly recognize”
Hippocampal neurogenesis: Opposing effects of stress and antidepressant treatment (2006, background): “Basic research has firmly established that neurogenesis persists in the adult mammalian brain (Kempermann et al., 1997; Eriksson et al., 1998; Gould et al., 1999; Gage, 2000;).”
Why New Neurons? Possible Functions for Adult Hippocampal Neurogenesis (2002, background): “Since then a number of studies have extended these findings (Gould et al., 1999b; Nilsson et al., 1999; Van Praag et al., 1999b), and it became evident that the mammalian hippocampus does indeed show an activity-dependent regulation of adult neurogenesis similar to that seen in birds.”
New neurons in the dentate gyrus are involved in the expression of enhanced long‐term memory following environmental enrichment (2005, methodology): “For example, training on hippocampaldependent learning tasks specifically enhances survival of adultgenerated neurons in the rat dentate gyrus (Gould et al., 1999a) and, conversely, the reduction of neurogenesis by a cytostatic drug impairs associative hippocampal-dependent, but not…”
A computational model of pattern separation efficiency in the dentate gyrus with implications in schizophrenia (2015, background): “It is believed that the DG is involved in learning and memory (Gould et al., 1999).”
Learning Enhances the Survival of New Neurons beyond the Time when the Hippocampus Is Required for Memory (2004, methodology): “However, it may be the relative immaturity of these cells that qualifies them for functions that more mature cells cannot accomplish ( Gould et al., 1999b; Gould and Gross, 2002).”
A computational principle for hippocampal learning and neurogenesis (2005, background): “…are likely an underestimate of what would be observed in more natural settings, because many environmental factors including associative learning (Gould et al., 1999a,b), locomotion (van Praag et al., 1999), and environmental enrichment (Kempermann et al., 1997) have been shown to increase the…”
The developing brain and neural plasticity: Implications for normality, psychopathology, and resilience. (2015, background): “In a study that has generated a great deal of controversy in the literature, Gould et al. (1999) discovered that stress does not alter the survival of recently produced neurons in the dentate gyrus.”
Neurogenesis in the adult brain: death of a dogma (2000, background): “, also impair hippocampal-dependent learning such as spatial learning in a water maz”
Neurogenesis may relate to some but not all types of hippocampal‐dependent learning (2002, background): “For example, learning of some hippocampal-dependent tasks, such as trace eyeblink conditioning and spatial navigation in the Morris water maze, increases the number of new granule cells by enhancing either cell survival or proliferation (Gould et al., 1999a; Lemaire et al., 2000).”
A hypothesis about the role of adult neurogenesis in hippocampal function. (2004, background): “The discovery of adult hippocampal neurogenesis has led to the notion that new neurons might play a critical role in learning and memory processing (13).”