Hippocampal neurogenesis: Opposing effects of stress and antidepressant treatment

By J. Warner-Schmidt, R. Duman. 2006

822 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience

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Citations in the corpus

Modification of hippocampal circuitry by adult neurogenesis (2012, background): “…have also been shown to regulate adult hippocampal neurogenesis by increasing neural progenitor proliferation, accelerating dendritic development, and enhancing survival of newborn neurons, presumably though indirect modulation of the niche (Warner-Schmidt and Duman, 2006; Sahay and Hen, 2007).”
The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior (2007, background): “BDNF and VEGF increase neurogenesis in the adult hippocampus by regulating survival and proliferation of newborn neurons, respectively (Warner-Schmidt and Duman, 2006).”
Role of neurotrophic factors in depression. (2007, background): “Stressed animals and depressed patients show reduced volume of the hippocampus, and at least part of this effect can be counteracted by antidepressant drugs [8,10].”
Depression: An Evolutionarily Conserved Mechanism to Terminate Separation Distress? A Review of Aminergic, Peptidergic, and Neural Network Perspectives (2009, background): “…guided by how depression is related to important alterations of the HPA axis (e.g., hypercortisolemia, which promotes hippocampal atrophy); it is rarely made clear how such changes may be related to the affective changes of depression (Drew & Hen, 2007; McEwen, 2004; Warner-Schmidt & Duman, 2006).”
Gray matter abnormalities in Major Depressive Disorder: a meta-analysis of voxel based morphometry studies. (2012, background): “It has been suggested that that these subtle hippocampal reductions reflect stressrelated changes associated with recurrent depressive episodes (MacQueen et al., 2003; Warner-Schmidt and Duman, 2006).”
Mechanisms and functional implications of adult neurogenesis. (2008, neutral): “The transcription factor cAMP-response element-binding protein (CREB) is an intracellular effector of monoamine, BDNF, and VEGF signaling pathways (reviewed in Warner-Schmidt and Duman, 2006).”
The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity (2010, background): “…been shown to increase neurogenesis and survival of newborn neurons in the hippocampal dentate gyrus (Madsen et al., 2000; Malberg et al., 2000; Warner-Schmidt and Duman, 2006) and in some cases, neurogenesis appears to be important for the behavioral effects of antidepressant drugs…”