Widespread Translational Inhibition by Plant miRNAs and siRNAs

By P. Brodersen, Lali Sakvarelidze-Achard, M. Bruun-Rasmussen, P. Dunoyer, Yoshiharu Y. Yamamoto, L. Sieburth, Olivier Voinnet. Science, 2008

1,459 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/743b15e148e4732a48bf0b2916ea87d8b51162a8

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Citations in the corpus

Uncovering Small RNA-Mediated Responses to Phosphate Deficiency in Arabidopsis by Deep Sequencing1[W][OA] (2009, background): “[OA] Open Access articles can be viewed online without a subscription. www.plantphysiol.org/cgi/doi/10.1104/pp.109.147280 2120 Plant Physiology , December 2009, Vol. 151, pp. 2120–2132, www.plantphysiol.org 2009 American Society of Plant Biologists be common as well (Brodersen et al., 2008).”
DNA methylation mediated by a microRNA pathway. (2010, background): “…miRNAs repress their target gene expression primarily through mRNA cleavage (Llave et al., 2002; Voinnet, 2009), with a subset of them also repressing translation (Aukerman and Sakai, 2003; Brodersen et al., 2008; Chen, 2004; Dugas and Bartel, 2008; Gandikota et al., 2007; Lanet et al., 2009).”
Degradome sequencing reveals endogenous small RNA targets in rice (Oryza sativa L. ssp. indica) (2010, background): “Recently, small RNA mediated translational repression was also recognized as a widespread mode of action in higher plants (Brodersen et al., 2008).”
The Functions of MicroRNAs: mRNA Decay and Translational Repression. (2015, background): “involved in translational repression [117].”
Regulation of OsSPL14 by OsmiR156 defines ideal plant architecture in rice (2010, positive): “Recent studies also showed that the translation inhibition of targets by miRNA was widespread in higher plant”
Small silencing RNAs: an expanding universe (2009, positive): “Nonetheless, AGO1-loaded plant miRNAs can also block translation, suggesting a common mechanism between plant and animal miRNAs, despite the absence of specific miRNAs shared between the two kingdom”
Control of Jasmonate Biosynthesis and Senescence by miR319 Targets (2008, background): “with the field [4], much of the available evidence suggests that”
Small RNA sorting: matchmaking for Argonautes (2010, background): “However, recent studies have indicated that cleavage-independent translational repression is widespread in plants, even for highly complementary target site”
Evolution and Functional Diversification of MIRNA Genes (2011, background): “Alternatively, young miRNAs could function primarily through nondegradative mechanisms that cannot be assayed by measuring target transcript abundance (Brodersen et al., 2008; Lanet et al., 2009).”
Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells. (2009, background): “It has since become evident that these RNAs may also strongly downregulate translation, with only a minimal effect on mRNA levels [87–89].”
Small RNAs and Their Roles in Plant Development (2009, background): “AGO1, AGO10, a microtubule-severing enzyme, and Pbody components are all required for miRNA-mediated translational inhibition (Brodersen et al. 2008).”
TAPIR, a web server for the prediction of plant microRNA targets, including target mimics (2010, background): “Recent studies have shown that translational repression mediated by miRNAs is more frequent than previously thought in plants (Brodersen et al., 2008; Brodersen and Voinnet, 2009; Dugas and Bartel, 2008).”
Revisiting the principles of microRNA target recognition and mode of action (2009, background): “thaliana identified mutants in which silencing by several distinct miRNAs with highly matched targets is defective at the protein level, despite normal repression of their endogenous mRNA target”
psRNATarget: a plant small RNA target analysis server (2011, background): “Recent discoveries suggest that plant miRNA may inhibit gene expression at the translational level (11), *To whom correspondence should be addressed.”