Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells.
By M. Chekulaeva, W. Filipowicz. Current Opinion in Cell Biology, 2009
722 citations recorded by the source corpus.
Subfields: Cancer Research, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/a93cdbbba229b04beae94f72a8dad3fa87cc014a
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Cancer Research
- David Baltimore
- D. Rao
- Ryan M. O’Connell
- Aadel A Chaudhuri
- Nahum Sonenberg
- M. Fabian
- S. Barik
- M. Gorospe
In Molecular Biology
- David Baltimore
- Ryan M. O’Connell
- D. Rao
- Aadel A Chaudhuri
- Nahum Sonenberg
- Marc R. Friedländer
- W. Filipowicz
- M. Fabian
Citations in the corpus
- The widespread regulation of microRNA biogenesis, function and decay (2010, background): “During the past decade we have learned much about the basic mechanisms of miRNA biogenesis and functio”
- miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades (2011, background): “This effector complex then either reduces the stability of the mRNA or inhibits its translation (2).”
- Regulation of mRNA translation and stability by microRNAs. (2010, background): “It is difficult to conclude whether the reported discrepancies are artifacts of different experimental approaches or whether miRNAs are indeed able to exert their repressive effects by disparate mechanisms (5, 8, 9, 23).”
- MicroRNAs: Processing, Maturation, Target Recognition and Regulatory Functions. (2011, background): “Intriguingly, recent evidence showed that miRNAs may target the promoter regions as well (48) and have the potential to activate gene expression (95).”
- Physiological and pathological roles for microRNAs in the immune system (2010, background): “The miRNA then guides the RISC to its target 3′ UTRs, leading to inhibition of translation and/or a decrease in mRNA stability as a result of accelerated uncapping and deadenylatio”
- LincRNA-p21 suppresses target mRNA translation. (2012, background): “Small ncRNAs, particularly microRNAs (miRNAs), partially base pair with specific target mRNAs and repress their expression by lowering mRNA stability and/or translation (Chekulaeva and Filipowicz, 2009; Guo et al., 2010).”