Conjugated Linoleic Acid Is Synthesized Endogenously in Lactating Dairy Cows by Δ9-Desaturase

By J. Griinari, B. Corl, S. H. Lacy, P. Chouinard, K. Nurmela, D. Bauman. 2000

1,050 citations recorded by the source corpus.

Subfields: Biochemistry, Endocrinology, Diabetes and Metabolism, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/6ee8dd648136e0e35d87fb5c8e60d1b9dcc23366

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In Biochemistry

1. P. Garnsworthy
2. R. G. Jensen
3. J. Rouel
4. K. Shingfield
5. Y. Chilliard
6. A. Ferlay

In Endocrinology, Diabetes and Metabolism

1. J. Rouel
2. K. Shingfield
3. Y. Chilliard
4. A. Ferlay

In Nutrition and Dietetics

1. Y. Chilliard
2. J. Rouel
3. M. Doreau
4. S. Smet
5. K. Shingfield
6. A. Ferlay
7. P. Garnsworthy
8. R. G. Jensen

Citations in the corpus

• Effect of dietary fatty acids on incorporation of long chain polyunsaturated fatty acids and conjugated linoleic acid in lamb, beef and pork meat: a review (2004, background): “However, since the endogenous production of c9t11CLA should probably be more important than its ruminal production (Griinari et al., 2000; Raes et al., 2003c), increased production of its precursor t11C18:1 in the rumen during biohydrogenation of LA or LNA is thought to be responsible for these…”
• Innovations in beef production systems that enhance the nutritional and health value of beef lipids and their relationship with meat quality. (2006, background): “However, Griinari et al. (2000) and Palmquist (2001) showed that the primary source of CLA cis-9, trans-11 is endogenous synthesis from TVA formed during ruminal biohydrogenation and involving D9-desaturase (Khanal & Dhiman, 2004; Song & Kennelly, 2003).”
• Feeding strategies to design the fatty acid profile of sheep milk and cheese (2014, background): “In addition, C18:2 c9, t11 CLA in milk originates partially from the ruminal biohydrogenation of C18:2 as an intermediate rumen product and mainly (from 64 to 98%) from endogenous synthesis from VA in the mammary gland by Delta-9-desaturase activity (Griinari et al., 2000; Piperova et al., 2002).”
• Increasing the concentrations of beneficial polyunsaturated fatty acids in milk produced by dairy cows in high-forage systems (2006, background): “Because trans-11 18:1 can also be converted to cis-9, trans-11 CLA via stearoyl-CoA desaturase activity in the mammary gland, and endogenous synthesis is quantitatively the most important source of this CLA isomer secreted in milk fat (Griinari et al., 2000; Corl et al., 2001; Piperova et al., 2002;”
• Diet-induced milk fat depression: Association with changes in milk fatty acid composition and fluidity of milk fat (2008, methodology): “Milk fat was extracted using the method of Hara and Radin (1978) and fatty acid methyl esters were prepared by base-catalyzed transmethylation according to Christie (1982).”
• Biosynthesis of Conjugated Linoleic Acid (CLA): A Review (2004, neutral): “Griinari et al. (2000) subsequently examined the potential for endogenous synthesis of CLA by infusing TVA abomasally and measuring the changes in milk fat CLA.”
• Effect of a grass-based and a concentrate feeding system on meat quality characteristics and fatty acid composition of longissimus muscle in different cattle breeds (2005, background): “Griinari et al. (2000) demonstrated that CLAcis-9,trans-11 can be produced by endogenous synthesis from C18:1trans-11 by the enzyme D9desaturase.”