Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system.

By B. Reynolds, S. Weiss. 1992

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Citations in the corpus

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions (2011, background): “Multipotent neural stem cells were later derived from the adult mammalian brain (Reynolds and Weiss, 1992; Richards et al., 1992).”
Prox1 Is Required for Granule Cell Maturation and Intermediate Progenitor Maintenance During Brain Neurogenesis (2010, methodology): “Neurosphere cultures were established as described, with modifications”
Visualization and genetic manipulation of adult neurogenesis using transgenic mice (2011, background): “…stem cells, nestin is now widely known as an intermediate filament protein that is expressed in both neural and non-neural tissue (Lendahl et al., 1990; Reynolds & Weiss, 1992; Reynolds et al., 1992; Zimmerman et al., 1994; Johansson et al., 2002; Wiese et al., 2004; Chojnacki et al., 2009).”
Peripheral Infusion of IGF-I Selectively Induces Neurogenesis in the Adult Rat Hippocampus (2000, background): “However, self-renewing cells with multilineage potential, designated stem cells or progenitor cells, have been identified in the adult mammalian brain (Reynolds and Weiss, 1992; Richards et al., 1992; Craig et al., 1996; Suhonen et al., 1996; McKay, 1997; Temple and Alvarez-Buylla, 1999).”
Isolation of cancer stem cells from adult glioblastoma multiforme (2004, methodology): “All the six monolayer-growing adult glioblastoma cells were switched into a defined serum-free NSC medium (Reynolds and Weiss, 1992) containing 20 ng/ml of basic fibroblast growth factor (bFGF, Peprotech, Rocky Hill, NJ, USA), 20 ng/ml of epidermal growth factor (EGF, Peprotech) and 20 ng/ml…”
The development of neural stem cells (2001, background): “After the discovery of neural stem cells in the embryo, the first isolation of stem-like cells from adult brai”
Isolation of multipotent adult stem cells from the dermis of mammalian skin (2001, background): “gif" NDATA ITEM> ]> Adult stem cells have been isolated from several tissue sources, including the central nervous syste”
Delayed Transplantation of Adult Neural Precursor Cells Promotes Remyelination and Functional Neurological Recovery after Spinal Cord Injury (2006, methodology): “Similar to embryonic stem cells (ESCs), adult neural precursor cells (NPCs) have shown an extensive capacity for self-renewal and multipotency in vitro (Reynolds and Weiss, 1992; Richards et al., 1992), and, importantly, they obviate the potential ethical issues surrounding the use of ESCs for regen”
Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations. (2001, background): “…that cells derived from rodent fetal brain or adult SVZ or adult DG cells can grow in vitro in the presence of defined factors such as bFGF and EGF (Reynolds & Weiss 1992, Richards et al. 1992, Temple & Alvarez-Buylla 1999, Temple & Davis 1994, Gritti et al. 1996, Johe et al. 1996, Kalyani et al.…”
GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain (2004, background): “Adult multipotent neurospheres express reporter protein Putative adult neural progenitors can be isolated from the adult forebrain and grown in vitro as sphere-forming cell colonie”
Adult neurogenesis and cellular brain repair with neural progenitors, precursors and stem cells (2006, background): “…are significant numbers of multipotent neural precursors, or ‘stem cells’, in many parts of the adult mammalian brain (Altman & Das 1965; Altman 1969; Reynolds & Weiss 1992; Lois & Alvarez-Buylla 1993; Palmer et al. 1995; and see reviews in McKay (1997), Gage (2000), van der Kooy & Weiss (2000)…”
Radial glia cells are candidate stem cells of ependymoma. (2005, background): “Ependymomas contain rare populations of RGC-like cells that self-renew and are multipotent in culture Normal and malignant neural stem cells may be isolated in culture as clonally derived colonies termed neurospheres (Reynolds and Weiss, 1992).”