Correlation Between Histone Lysine Methylation and Developmental Changes at the Chicken β-Globin Locus

By Michael D. Litt, M. Simpson, M. Gaszner, C. D. Allis, G. Felsenfeld. Science, 2001

643 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/614764406747e7f8ea4afc1d680b2d0d0562c483

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Citations in the corpus

A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5′ flanking region of SMYD3 is a risk factor for human cancers (2005, background): “Methylation of H3 Lys4 is frequently observed in transcriptionally active regions of the human genome; trimethylation of H3 Lys4 changes the chromatin structure, leading to transactivation of target gene”
Histone H3 lysine 4 methylation patterns in higher eukaryotic genes (2004, result): “Overall, our observations with the β-globin genes agree with earlier correlations of di-methyl K4/H3 with gene activity in the chicken β-globin locu”
Insulators: exploiting transcriptional and epigenetic mechanisms (2006, background): “The chromosomal position of cHS4 is marked in all cell types by a nuclease-hypersensitive site and a peak of euchromatin-specific histone modifications (histone acetylation and H3K4 methylation”
The profile of repeat‐associated histone lysine methylation states in the mouse epigenome (2005, background): “…a histone modification map of the mouse epigenome Profiling analyses for histone lysine methylation have been performed on defined chromosomal loci (Litt et al, 2001; Noma et al, 2001), parts of entire chromosomes (Greil et al, 2003; Lippman et al, 2004) and with genome-wide but promoter-biased or…”
The circuitry of a master switch: Myod and the regulation of skeletal muscle gene transcription (2005, background): “…association of DNase hypersensitivity and histone modifications with the hemoglobin gene in red blood cell nuclei but not in nuclei from other cells (Litt et al., 2001; Weintraub and Groudine, 1976) – suggested that developmentally established chromatin modifications can determine the genes that…”
Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae. (2001, background): “Several reports have suggested that H3 methylation is coupled to acetylation (Hendzel and Davie 1991; Annunziato et al. 1995; Strahl et al. 1999; Litt et al. 2001), but a mechanistic link between H3 Lys4 methylation and H3 lysine acetylation has yet to be shown (Jenuwein and Allis 2001).”
Genomic maps and comparative analysis of histone modifications in human and mouse. (2005, methodology): “QuantitativeCambridge, Massachusetts 02139 PCR-based approaches have been used to map histone modification patterns at the -globin locus in mouse and chicken (Bulger et al., 2003; Litt et al., 2001; Schneider etSummary al., 2004).”
The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases. (2007, positive): “Histone H3K4 trimethylation positively regulates transcription (Liang et al., 2004; Litt et al., 2001; Noma et al., 2001; Santos-Rosa et al., 2002; Schneider et al., 2004) in part by recruiting chromatin-remodeling complexes (Santos-Rosa et al.”
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. (2002, background): “A significant increase in methylated H3-K4 in G9a−/− cells was observed (Figs.”
Histone and chromatin cross-talk. (2003, background): “By contrast, euchromatic regions largely appear to be hyperacetylated and methylated on H3-K4 [74].”