High-fat diet disrupts behavioral and molecular circadian rhythms in mice.

By A. Kohsaka, A. Laposky, K. Ramsey, Carmela L. Estrada, C. Joshu, Yumiko Kobayashi, F. Turek, J. Bass. Cell Metabolism, 2007

1,495 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Endocrine and Autonomic Systems

View Paper: https://www.semanticscholar.org/paper/5f2cf2549dbfaac421eab760aab18bd7a0b43bcc

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In Cellular and Molecular Neuroscience

In Endocrine and Autonomic Systems

Citations in the corpus

Time-restricted feeding is a preventative and therapeutic intervention against diverse nutritional challenges (2014, background): “In HFD-induced obesity, such temporal regulation is blunted (Kohsaka et al., 2007).”
Metabolic regulation of epigenetics (2012, background): “Moreover, high-fat diet could alter animals’ daily rhythm and the cycling of circadian clock genes (Kohsaka et al., 2007).”
The Genetics of Mammalian Circadian Order and Disorder: Implications for Physiology and Disease (2008, background): “Interestingly, environmental modulators of metabolic state (for example, a high-fat diet) can subtly influence circadian period and the expression of cycling genes in mic”
Effects of diurnal variation of gut microbes and high fat feeding on host circadian clock function and metabolism (2015, neutral): “Contrary to the MBH responses, HF suppressed bmal1 expression in the liver (Figure 1E, ZT2, 18, and 22), blunting the hepatic CC pattern, as previously shown (Kohsaka et al., 2007; Eckel-Mahan et al., 2013).”
Reprogramming of the Circadian Clock by Nutritional Challenge (2013, positive): “Importantly, most of the core circadian genes were rhythmic in the livers of HFD-fed mice (Figure 4A), displaying only weak shifts or slightly dampened patterns of oscillation, results which are cohesive with previously published work (Hatori et al., 2012; Kohsaka et al., 2007).”
Circadian Timing of Food Intake Contributes to Weight Gain (2009, positive): “#ese results are consistent with previous studies (5), supporting the hypothesis that light phase feeding may be a critical component of weight gain.”
Time restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high fat diet (2012, positive): “However, they also exhibit dampened feeding and circadian rhythms (Kohsaka et al., 2007).”
Diet and Feeding Pattern Affect the Diurnal Dynamics of the Gut Microbiome (2014, neutral): “Mice with ad libitum access to normal chow (NA mice; Figure 1A) have a cyclical feeding pattern, eating most of their diet during their nighttime active phase and less during their daytime inactive phase (Hatori et al., 2012; Kohsaka et al., 2007; Liu et al., 2014).”
Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression (2009, background): “Discussion Circadian expression of several oscillator components in the mouse liver persist under prolonged fasting, daily restricted feeding (3), frequent meal (23), and high fat diet conditions (24).”
Light at night increases body mass by shifting the time of food intake (2010, background): “Furthermore, consumption of a high-fat diet alters circadian rhythmicity and the cycling of circadian clock genes in mice (13).”
A smartphone app reveals erratic diurnal eating patterns in humans that can be modulated for health benefits (2015, background): “Benefits persisted for a year.”