Regulatory T cells and mechanisms of immune system control

By A. O’Garra, P. Vieira. Nature Medicine, 2004

898 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/59fadfabed1c6299890947f255bf4a555b558c0e

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In Immunology

1. A. O’Garra
2. Bali Pulendran
3. P. Vieira
4. H. von Boehmer
5. M. Saraiva
6. Rafi Ahmed
7. C. Hawrylowicz
8. S. Rivest

Citations in the corpus

• The regulation of IL-10 production by immune cells (2010, background): “, but further evidence suggested that the production of IL-10 was associated with tolerant or regulatory T (T Reg ) cell response”
• Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma (2005, background): “Regulatory T-cell subsets Regulatory or suppressor T cells are cells that inhibit inflammatory pathologies in vivo , and they have also been shown to control T-cell proliferation and cell number in vitro and in vivo”
• TH1 cells control themselves by producing interleukin-10 (2007, background): “Compatible with this role is the observation that although IL-10-deficient mice may clear certain intracellular pathogens more efficiently, this is often accompanied by lethal immunopatholog”
• Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke (2009, background): “They are capable of modulating the function of effector T cells, they alter the activity of antigen-presenting cells via direct interaction and they secrete anti-inflammatory molecules, including IL-10 and TGF-&beta”
• Inflammatory mechanisms in ischemic stroke: role of inflammatory cells (2010, neutral): “ing anti-inflammatory cytokines (IL-10, TGF- ) [94, 95].”
• Innate and adaptive immunity in inflammatory bowel disease. (2014, background): “Regulatory T cells (Treg), characterized by the expression of Foxp3, may be defined as T cells able to suppress Th0 cell proliferation both in vitro and in vivo [80].”
• Translating innate immunity into immunological memory: implications for vaccine development. (2006, background): “As discussed above, a hallmark of adaptive immunity is the existence of qualitatively different types of responses, such as Th1, Th2, and T regulatory responses (O'Garra and Robinson, 2004; Mowen and Glimcher, 2004; O'Garra and Vieira, 2004).”
• Mechanisms of suppression by suppressor T cells (2005, background): “Although the focus of this review is on CD4 + CD25 + suppressor T cells with high Foxp3 expression, other CD4 (refs”