Translating innate immunity into immunological memory: implications for vaccine development.

By Bali Pulendran, Rafi Ahmed. Cell, 2006

680 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/d035dfc8fdbd70c235c9069c3cc89413c3eaafea

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. Jacques Banchereau
2. M. Karin
3. T. Lawrence
4. V. Nizet
5. W. Nicholas Haining
6. Rafi Ahmed
7. B. Guy
8. A. Palucka

In Molecular Biology

1. M. Karin
2. T. Lawrence
3. B. Guy
4. Rafi Ahmed
5. Theam Soon Lim
6. Jacques Banchereau
7. R. Medzhitov
8. N. Perkins

Citations in the corpus

• Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. (2006, background): “Crosstalk between the innate and adaptive immune system is extensively reviewed by Pulendran and Ahmed (2006) in this issue of Cell and will not be discussed further here, but as outlined below, a switch from an acute but short-lived inflammatory response driven by granulocytes and macrophages to a…”
• Naïve Human Antibody Libraries for Infectious Diseases (2018, background): “Defective CSR has been associated with a range of diseases [43] [44] [45] .”
• The perfect mix: recent progress in adjuvant research (2007, background): “Finally, T- and B-cell memory responses have also been dissected, allowing the identification of various means of inducing different subsets of memory cells with distinct function”
• Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo. (2010, result): “This suggests that memory cells differentiate from effector cells and is consistent with the proposal that (Kolumam et al., 2005; Pulendran and Ahmed, 2006) direct action of type I interferons on CD8 T cells promotes CD8 T cell expansion and survival, thus resulting in the generation of a stable poo”
• The evolution of adaptive immune systems. (2006, neutral): “Having evolved in the presence of well-established innate immunity, our adaptive immune system is designed to work well in conjunction with innate immune mechanisms (Pulendran and Ahmed, 2006 [this issue of Cell ]).”
• Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cells. (2008, background): “Yet these mmunity 29, 497–510, September 19, 2008 ª2008 Elsevier Inc. 507 vaccines are all specific for acute infections, and their protective capacity arises largely from their induction of humoral immune responses (Pulendran and Ahmed, 2006).”