Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens.

By C. Nathan, M. Shiloh. Proceedings of the National Academy of Sciences of the United States of America, 2000

1,518 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/575ee2415035c44c0f1ffc1de85232e1c3e26783

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Citations in the corpus

Peroxynitrite reductase activity of bacterial peroxiredoxins (2000, background): “Host defence against experimental tuberculosis depends on production of reactive nitrogen intermediates by NOS”
The immune response in tuberculosis. (2013, background): “Although iNOS-expressing macrophages have been identified in the lungs of humans with TB (273), the correlation between human TB and iNOS expression is still unclear (274).”
Myeloperoxidase: friend and foe (2005, background): “However, human neutrophils appropriately stimulated have been shown to contain an inducible NO· synthase (iNOS) [282–284], as do tissue macrophages from infected humans [285–288].”
Penaeid Shrimp Immune System (2009, background): “developed including enzymatic substance (catalase, glutathione peroxidase (GPx), and SOD) and nonenzymatic components (ascorbate, β-carotene, flavonoids, α-tocopherol and vitamin E), which may neutralize the ROIs or repair the molecular damage done to the cell (Nathan and Shiloh, 2000).”
Nitrate, bacteria and human health (2004, background): “This newly described pathway for the generation of reactive nitrogen intermediates (RNIs) in mammals complements the production of RNIs by nitric oxide synthase (NOS) in white blood cell”
Toll-like receptors and cancer (2009, background): “and optimize microbial killing through the generation of reactive oxygen and nitrogen intermediates and stimulation of the neutrophil oxidative burs”
Macrophage defense mechanisms against intracellular bacteria (2015, background): “Using arginine and oxygen, the homodimeric NOS2 generates NO and citrulline, as one subunit transfers electrons between NADPH, FAD, flavin mononucleotide to the heme iron of the second subunit (56, 57).”
Biochemical and functional characterization of three activated macrophage populations (2006, background): “These cells are prototypical immune effector cells, which kill intracellular pathogens via the production of oxygen and nitrogen radicals [5].”
The emerging role of reactive oxygen and nitrogen species in redox biology and some implications for plasma applications to medicine and biology (2012, background): “Several authors point to the long history of hostpathogen ‘arms races’ in which each side seeks to gain an advantage [79, 86, 87].”
Phagocyte partnership during the onset and resolution of inflammation (2010, background): “Neutrophils are equipped with a large range of antimicrobial polypeptides that are readily stored in granules and can also rapidly produce oxygen radical”
Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages (2003, background): “Through a variety of cell surface receptors, macrophages internalize microbes into phagosomes that undergo maturational events that expose the microbes to acid, lytic enzymes, oxygenated lipids, fatty acids, and reactive oxygen and nitrogen intermediates (1, 2).”
Oxidative Stress, Prooxidants, and Antioxidants: The Interplay (2014, background): “Vice versa to this, different studies have proven that individuals deficient in antioxidative mechanism are more susceptible to severe bacterial and fungal infections as in case of HIV infections [125].”
Mycobacterium tuberculosis: Success through dormancy (2012, background): “Macrophages operate as prime defense cells against microbial intruders (Nathan & Shiloh, 2000; Liu & Modlin, 2008; Deretic et al., 2009).”