Drug abusers show impaired performance in a laboratory test of decision making.

By S. Grant, C. Contoreggi, E. London. Neuropsychologia, 2000

656 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/3be2996373887b34f352d63591ad1675b8ae460d

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In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

In Psychiatry and Mental health

Citations in the corpus

Decision-making in disinhibited adolescents and adults: Insensitivity to future consequences or driven by immediate reward? (2003, result): “The finding that cognitively disinhibited individuals perform worse on the standard ICGT is consistent with the results reported previously in studies examining individuals who are arguably cognitively disinhibited, such as Grant et al. (2000) and Bechara et al. (2001).”
Orbitofrontal cortex dysfunction in abstinent cocaine abusers performing a decision-making task (2003, background): “Substance abusers also show performance deficits on this task (Bartzokis et al., 2000; Grant et al., 2000).”
Decreased gray matter concentration in the insular, orbitofrontal, cingulate, and temporal cortices of cocaine patients. (2002, neutral): “Another study showed that drug abusers perform only half as well as control subjects on the gambling task (Grant et al 2000).”
Decision-making and addiction (part II): myopia for the future or hypersensitivity to reward? (2002, methodology): “Using a decision-making instrument known as the “gambling task” (GT), as a tool for measuring decision-making, most substance dependent individuals (SDI) behaved in such a way that they opted for choices that yielded high immediate gains in spite of higher future losses [7,30,42].”
Decision-making and addiction (part I): impaired activation of somatic states in substance dependent individuals when pondering decisions with negative future consequences. (2002, result): “This is consistent with recent findings showing impairment on the GT in cocaine [2,8,26], opiate [41], and alcohol [37] abusers.”
Neural substrates of faulty decision-making in abstinent marijuana users (2005, background): “, 2004) and in abusers of alcohol, cocaine, heroin, and methamphetamine (Bartzokis et al., 2000; Bechara et al., 2001; Bolla et al., 2003; Grant et al., 2000; Petry et al., 1998).”
Loss of willpower: Abnormal neural mechanisms of impulse control and decision making in addiction (2005, methodology): “…by finding a relationship between substance abuse and poor decision-making as measured by the Iowa Gambling Task (IGT), as well as other similar decision-making tasks (Bartzokis et al., 2000; Grant et al., 1997, 2000; Grant et al., 1999; Mazas et al., 2000; Petry et al., 1998; Rogers et al., 1999).”
Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective (2005, background): “These deficits were linked to the decision making impairments of VMPC patients when cocaine addicts were shown to make poor decisions on the Iowa Gambling Tas”
Evaluation of a behavioral measure of risk taking: the Balloon Analogue Risk Task (BART). (2002, methodology): “As a measure of risk propensity regarding drug use, we examined polydrug use (e.g., Babor et al., 1992; Grant et al., 2000), defined as the number of drug classes tried over the past 12 months across the following categories: (a) marijuana, (b) stimulants, (c) cocaine, (d) hallucinogens, (e)…”
Different underlying impairments in decision-making following ventromedial and dorsolateral frontal lobe damage in humans. (2004, background): “Abnormal IGT performance has been reported in substance abusers, compulsive gamblers, and psychopaths (Petry et al., 1998; Mitchell, 1999; Grant et al., 2000; Bechara et al., 2001, 2002; Cavedini et al., 2002) and has been taken as evidence for VMF dysfunction in these populations.”
Decision-making deficits, linked to a dysfunctional ventromedial prefrontal cortex, revealed in alcohol and stimulant abusers. (2001, methodology): “Second, functional neurolmaging studies using positron emission tomography (PET) indicate that the VM area is active during the performance of the gambling task [ 23 ].”