Decision-making deficits, linked to a dysfunctional ventromedial prefrontal cortex, revealed in alcohol and stimulant abusers.

By Antoine Bechara, Sara L. Dolan, N. Denburg, Andrea R. Hindes, S. Anderson, P. Nathan. Neuropsychologia, 2001

1,175 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Experimental and Cognitive Psychology

View Paper: https://www.semanticscholar.org/paper/144d2897646d15a9fc72ef9aaaf7b0496d3616b0

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In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

In Experimental and Cognitive Psychology

Citations in the corpus

Different underlying impairments in decision-making following ventromedial and dorsolateral frontal lobe damage in humans. (2004, background): “Keywords: dorsolateral prefrontal cortex, gambling, lesion, reversal learning, ventromedial prefrontal cortex”
Decision-making and addiction (part I): impaired activation of somatic states in substance dependent individuals when pondering decisions with negative future consequences. (2002, methodology): “Finally, it is important to note that we have shown that the decision-making impairment in VM patients is characterized by insensitivity to future consequences, positive and negative, such that their behavior is always guided by immediate contingency [8].”
The somatic marker hypothesis: a critical evaluation. (2006, result): “Bechara et al. (2001a) findings are also equally consistent with the idea that dopamine mediates exploratory behaviour (Montague et al., 2004), so do not offer exclusive support for the SMH. O'Carroll and Papps (2003) compared IGT performance in 30 healthy adult participants either administered a…”
Impulsivity and Substance Abuse: What Is the Connection? (2002, background): “It has been hypothesized that impulsivity may be an important factor in the switch between casual drug use and dependence, where the drug is used in spite of the negative consequences.(87) Likewise, there is a growing body of evidence that substances of abuse can increase impulsivity, both acutely a”
The role of impulsive behavior in drug abuse (2008, background): “The results of the studies described above could also have been explained by a third factor (H3) such as cognitive deficits in working memory (Hester and Garavan 2004) and decision-making (Bechara et al. 2001) that may contribute to impaired inhibition in drug abusers.”
Developmental neurocircuitry of motivation in adolescence: a critical period of addiction vulnerability. (2003, background): “Impulsive response patterns have been identified in association with impulsecontrol disorders, substance use disorders, and psychiatric diagnoses with impulse-control disorder and/or substance use disorder comorbidity (26, 33).”
Overreaction to Fearsome Risks (2011, neutral): “15 Jon Elster has explored the possibility that the worst-case analysis still should be employed as a maximin approach when the probabilities of the various outcomes cannot be assessed (Elster 1983).”
Decreased activation of lateral orbitofrontal cortex during risky choices under uncertainty is associated with disadvantageous decision-making and suicidal behavior (2010, positive): “In addition, several psychiatric disorders are also characterized by impaired decision-making including substance abuse (Bechara et al., 2001), psychopathy (Mitchell et al., 2002), outward aggression (Best et al., 2002) and suicidal behavior (Jollant et al., 2005; Malloy-Diniz et al., 2009;…”
Decision-making and addiction (part II): myopia for the future or hypersensitivity to reward? (2002, methodology): “This cut off score was determined from normal distribution curves comparing the performance of populations of normal control subjects, SDI, and VM patients on the GT [4,7].”