Oxidative stress and cell signalling.

By G. Poli, G. Leonarduzzi, F. Biasi, E. Chiarpotto. Current Medicinal Chemistry, 2004

739 citations recorded by the source corpus.

Subfields: Biochemistry, Organic Chemistry

View Paper: https://www.semanticscholar.org/paper/356222c3cb0e81d2c6279abe7a34af28368f29b1

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. K. Rahman
2. M. Valko
3. C. Rhodes
4. E. Kurutaş

In Organic Chemistry

1. M. Valko
2. K. Rahman
3. E. Kurutaş
4. Wen-Sheng Wu
5. K. Jomová

Citations in the corpus

• Mechanisms of nanotoxicity: Generation of reactive oxygen species (2014, background): “[47] Poli G, Leonarduzzi G, Biasi F, et al.”
• Regulation of Autophagy by Reactive Oxygen Species (ROS): Implications for Cancer Progression and Treatment (2009, neutral): “ROS can act as second messengers in the regulation of various cellular processes by oxidation of cysteine residues on target molecules, including kinases and phosphatases (21), redox-sensitive transcription factors (104), cell-cycle regulators (93), and cell membrane lipids (88).”
• The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state (2015, background): “Signal transduction is a process enabling information to be transmitted from the outside of a cell to various functional elements inside the cell [37].”
• Oxidative Stress and Antioxidant Defense (2012, background): “ROS can induce expression of several genes involved in signal transduction.(1,130) A high ratio for GSH/GSSG is important for the protection of the cell from oxidative damage.”
• The Role of Metallothionein in Oxidative Stress (2013, background): “they may be important mediators of damage to cell structures, including lipids and membranes, proteins and nucleic acids, when oxidative stress occurs [4].”
• Oxidative Stress, Prooxidants, and Antioxidants: The Interplay (2014, background): “Each cell in the human body maintains a condition of homeostasis between the oxidant and antioxidant species [53].”
• The signaling mechanism of ROS in tumor progression (2007, background): “tor [88] and cell membrane lipids [89] of which PKC and protein tyrosine phosphotase (PTP) are the most relevant to tumor cell invasion.”
• METHAMPHETAMINE TOXICITY AND MESSENGERS OF DEATH (2009, background): “…and cytokines might exert their physiological and pathological effects by influencing the expression of several transcriptional factors with long-term consequences on the brain’s molecular programming (Malemud and Miller, 2008; Planas et al., 2006; Poli et al., 2004; Potashkin and Meredith, 2006).”
• Studies on free radicals, antioxidants, and co-factors (2007, background): “In contrast, at high concentrations, ROS can be mediate damage to cell structures, including lipids and membranes, proteins and nucleic acids; this damage is often referred as “oxidative stress” (Poli et al 2004).”
• Free radicals and antioxidants in normal physiological functions and human disease. (2007, background): “It has been clearly demonstrated that ROS interfere with the expression of a number of genes and signal transduction pathways and are thus instrumental in the process of carcinogenesis (Poli et al., 2004; Valko et al., 2006).”
• Free radicals, metals and antioxidants in oxidative stress-induced cancer. (2006, background): “Cells communicate with each other and respond to extracellular stimuli through biological mechanisms called cell signalling or signal transduction [4,135].”